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4-hydroxy-5-oxoproline, also known as 5-L-hydroxyproline or 4-hydroxy-L-threonine, is a non-proteinogenic amino acid and a metabolite of the collagen degradation pathway. It is formed by the hydroxylation of proline in collagen, and subsequent cleavage by prolyl oligopeptidase. 4-hydroxy-5-oxoproline is also a component of the gamma-glutamyl cycle, where it is synthesized and degraded as part of the pathway for glutathione synthesis and metabolism. It serves as a precursor for the synthesis of glutathione, an important antioxidant in cells, and plays a role in maintaining cellular redox balance. Additionally, 4-hydroxy-5-oxoproline has been implicated in several disease states, including heart disease, liver disease, and neurological disorders, and has potential as a biomarker for these conditions.

51163-89-4

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51163-89-4 Usage

Uses

Used in Biomarker Applications:
4-hydroxy-5-oxoproline is used as a biomarker for various disease states, including heart disease, liver disease, and neurological disorders, due to its implication in these conditions.
Used in Pharmaceutical Industry:
4-hydroxy-5-oxoproline is used as a precursor for the synthesis of glutathione, an important antioxidant in cells, for the development of pharmaceuticals targeting oxidative stress-related conditions.
Used in Research Applications:
4-hydroxy-5-oxoproline is used as a research tool for studying the collagen degradation pathway, the gamma-glutamyl cycle, and the role of glutathione in cellular redox balance.

Check Digit Verification of cas no

The CAS Registry Mumber 51163-89-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,1,6 and 3 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 51163-89:
(7*5)+(6*1)+(5*1)+(4*6)+(3*3)+(2*8)+(1*9)=104
104 % 10 = 4
So 51163-89-4 is a valid CAS Registry Number.

51163-89-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-hydroxy-5-oxopyrrolidine-2-carboxylic acid

1.2 Other means of identification

Product number -
Other names 4-hydroxy-5-oxo-proline

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:51163-89-4 SDS

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