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CAS

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51169-57-4

2-(1-hydroxyethyl)-3,4-dimethyl-1,3-thiazol-3-ium bromide, also known as thioflavin S, is a cationic fluorescent dye that selectively binds to beta-sheet-rich structures, such as amyloid fibrils, and exhibits enhanced fluorescence upon binding. It is commonly used in the study of protein aggregation and amyloid fibrils, making it a valuable tool in the detection and quantification of amyloid aggregates in various biological samples.

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  • 51169-57-4 Structure

  • Basic information

    1. Product Name: 2-(1-hydroxyethyl)-3,4-dimethyl-1,3-thiazol-3-ium bromide
    2. Synonyms:
    3. CAS NO:51169-57-4
    4. Molecular Formula: C7H12BrNOS
    5. Molecular Weight: 238.1453
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 51169-57-4.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-(1-hydroxyethyl)-3,4-dimethyl-1,3-thiazol-3-ium bromide(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-(1-hydroxyethyl)-3,4-dimethyl-1,3-thiazol-3-ium bromide(51169-57-4)
    11. EPA Substance Registry System: 2-(1-hydroxyethyl)-3,4-dimethyl-1,3-thiazol-3-ium bromide(51169-57-4)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 51169-57-4(Hazardous Substances Data)

51169-57-4 Usage

Uses

Used in Neurodegenerative Disease Research:
2-(1-hydroxyethyl)-3,4-dimethyl-1,3-thiazol-3-ium bromide is used as a diagnostic tool for studying neurodegenerative diseases such as Alzheimer's and Parkinson's. Its ability to selectively label and visualize amyloid fibrils helps researchers understand the pathology of these diseases and develop potential diagnostic and therapeutic strategies.
Used in Protein Misfolding Disorder Research:
In the field of protein misfolding disorders, 2-(1-hydroxyethyl)-3,4-dimethyl-1,3-thiazol-3-ium bromide is used as a research tool to investigate the formation and characteristics of amyloid fibrils, which are associated with various diseases caused by protein misfolding.
Used in Diagnostic Applications:
2-(1-hydroxyethyl)-3,4-dimethyl-1,3-thiazol-3-ium bromide is used as a diagnostic agent for detecting the presence of amyloid aggregates in biological samples, which can be indicative of certain diseases and conditions. Its enhanced fluorescence upon binding to beta-sheet structures allows for sensitive and specific detection methods.

Check Digit Verification of cas no

The CAS Registry Mumber 51169-57-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,1,6 and 9 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 51169-57:
(7*5)+(6*1)+(5*1)+(4*6)+(3*9)+(2*5)+(1*7)=114
114 % 10 = 4
So 51169-57-4 is a valid CAS Registry Number.

51169-57-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(3,4-dimethyl-1,3-thiazol-3-ium-2-yl)ethanol,bromide

1.2 Other means of identification

Product number -
Other names 2-HE-Dmt

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:51169-57-4 SDS

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