51186-35-7Relevant academic research and scientific papers
Parallel synthesis of "Click" chalcones as antitubulin agents
Utsintong, Maleeruk,Massarotti, Alberto,Caldarelli, Antonio,Theeramunkong, Sewan
, p. 510 - 516 (2013/07/28)
It has been shown that some chalcones are able to inhibit tubulin polymerization, giving cytotoxicity and destruction of tumoral vasculature. A library of 180 novel chalcone analogs has been synthesized via click chemistry and screened for their cytotoxic
COMPOSITIONS USEFUL AS INHIBITORS OF PROTEIN KINASES
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Page 47, (2008/06/13)
The present invention provides a compound of formula I: or a pharmaceutically acceptable salt or mixtures thereof. These compounds are inhibitors of protein kinases, particularly inhibitors of GSK mammalian protein kinase, and more particularly inhibitors
