5121-37-9Relevant academic research and scientific papers
New syntheses of (±)-lamprolobine and (±)-epilamprolobine
Michael,Jungmann
, p. 10211 - 10220 (2007/10/02)
(±)-Lamprolobine 1 and (±)-epilamprolobine 4 were prepared by a route featuring sulphide contraction of thiolactam 7 with bromoacetonitrile to give vinylogous cyanamide 8, reduction and ring closure to the unsaturated quinolizidine 11, and selective reduction of the latter to set up appropriate stereochemistry for the target alkaloids.
