51211-94-0Relevant articles and documents
Direct Determination of the Enantiomeric Purity of Chiral Trisubstituted Allenes by Using Permethylated Cyclodextrin as a Chiral Solvating Agent
Uccello-Barretta, Gloria,Balzano, Federica,Caporusso, Anna Maria,Salvadori, Piero
, p. 836 - 839 (1994)
The heptakis(2,3,6-tri-O-methyl)-β-cyclodextrin (TRIMEB) has been successfully used as convenient chiral solvating agent to determine the enantiomeric composition of chiral trisubstituted allenes by 1H NMR spectroscopy: the analysis of the effect of the molar ration TRIMEB/allene, temperature, and nature of the solvent allowed us to optimize the experimental conditions to enhance the separation between the signals of the two enantiomers of each allene.