51227-49-7 Usage
Chemical structure
Steroid compound
Medicinal use
Treatment of heart failure and certain types of irregular heartbeats
Classification
Cardiac glycoside
Source
Derived from the foxglove plant
Administration
Typically administered orally
Onset of action
Relatively slow, with peak effects occurring several hours after ingestion
Duration of action
Long
Blood level monitoring
Required due to its narrow therapeutic window
Side effects
Can have several side effects
Drug interactions
Can interact with other medications
Precaution
Should be used with caution and under the supervision of a healthcare professional
Please note that this list is based on the information provided in the material and may not be exhaustive. It is always recommended to consult a healthcare professional for accurate and up-to-date information on medications.
Check Digit Verification of cas no
The CAS Registry Mumber 51227-49-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,2,2 and 7 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 51227-49:
(7*5)+(6*1)+(5*2)+(4*2)+(3*7)+(2*4)+(1*9)=97
97 % 10 = 7
So 51227-49-7 is a valid CAS Registry Number.
InChI:InChI=1/C25H34O6/c1-14(26)31-20-12-25(29)19-5-4-16-11-17(27)6-8-23(16,2)18(19)7-9-24(25,3)22(20)15-10-21(28)30-13-15/h10,16,18-20,22,29H,4-9,11-13H2,1-3H3/t16-,18?,19?,20+,22?,23+,24-,25+/m1/s1
51227-49-7Relevant academic research and scientific papers
SYNTHESIS AND BIOLOGICAL ACTIVITY OF SOME CARDIOTONIC COMPOUNDS RELATED TO GITOXIGENIN
Humber, David C.,Jones, Paul S.,Phillipps, Gordon H.
, p. 19 - 30 (2007/10/02)
The four diastereomeric 3,16-diacetates 6, 9, 10 and 11 were prepared from gitoxin 1 by the routes shown in Schemes 1 and 2 and tested for inotropic activity in the isolated guinea-pig atrial preparation.In line with earlier findings in the digitoxigenin series, derivatives with a 3α-acetoxy function, viz 9 and 10, possessed high biological activity.
