51230-19-4 Usage
Uses
Used in Pharmaceutical Industry:
PYR-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-GLY-NH2 is used as a pharmaceutical agent for inducing ovulation and synchronizing the reproductive cycle in female rats, specifically Sprague-Dawley rats. This application is based on its ability to stimulate the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the anterior pituitary gland, which in turn promotes the development and maturation of ovarian follicles, leading to ovulation.
Additionally, the peptide can be used in research settings to study the effects of LH-RH on the reproductive system and to develop new therapeutic strategies for various reproductive disorders.
Biochem/physiol Actions
(D-Ala6)-LH-RH is a GnRH (gonadotropin-releasing hormone) agonist. GnRH, which is also referred to as LHRH (luteinizing hormone-releasing hormone) or gonadorelin, is crucial for mammalian reproduction and is released from hypothalamic neurons. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from pituitary glands. Mutations in GnRH are associated with normosmic congenital hypogonadotropic hypogonadism.
Check Digit Verification of cas no
The CAS Registry Mumber 51230-19-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,2,3 and 0 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 51230-19:
(7*5)+(6*1)+(5*2)+(4*3)+(3*0)+(2*1)+(1*9)=74
74 % 10 = 4
So 51230-19-4 is a valid CAS Registry Number.
