51244-88-3

Basic information

• Product Name: 1-{[(methylsulfanyl)acetyl]oxy}pyrrolidine-2,5-dione
• CAS NO: 51244-88-3
• Molecular Formula: C₇H₉NO₄S
• Molecular Weight: 203.2157
• Mol File: 51244-88-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 302.6°C at 760 mmHg
• Flash Point: 136.8°C
• Density: 1.4g/cm³
• Vapor Pressure: 0.000978mmHg at 25°C
• Refractive Index: 1.556
• CAS DataBase Reference: 1-{[(methylsulfanyl)acetyl]oxy}pyrrolidine-2,5-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-{[(methylsulfanyl)acetyl]oxy}pyrrolidine-2,5-dione(51244-88-3)
• EPA Substance Registry System: 1-{[(methylsulfanyl)acetyl]oxy}pyrrolidine-2,5-dione(51244-88-3)

Safety Data

• Hazardous Substances Data: 51244-88-3(Hazardous Substances Data)

Relevant articles and documents

A new parenteral cephalosporin. SK&F 59962: 7 trifluoromethylthioacetamido 3 (1 methyl 1H tetrazol 5 ylthiomethyl) 3 cephem 4 carboxylic acid. Chemistry and structure activity relationships

The synthesis, microbiological profile and in vivo effectiveness in laboratory animals of a series of cephalosporins having 7 acyl substituents derived from methylthioacetic acid are described. Structure activity relationships examined include the effect of oxidation of the side chain sulfur atom, replacement of the (side chain) methyl hydrogens by fluorine and replacement of the 3 acetoxy substituent by thioheterocycles. One derivative, 7 trifluoromethylthioacetamido 3 (1 methyl 1H tetrazol 5 ylthiomethyl) 3 cephem 4 carboxylic acid (SK and F 59962), was found to have outstanding antibacterial activity in vitro and in vivo.