51245-20-6

Basic information

• Product Name: (3E,6E)-3-but-2-en-1-ylidene-6-(phenylmethylidene)piperazine-2,5-dione
• CAS NO: 51245-20-6
• Molecular Formula: C₁₅H₁₄N₂O₂
• Molecular Weight: 254.2839
• Mol File: 51245-20-6.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 602.6°C at 760 mmHg
• Flash Point: 250.8°C
• Density: 1.251g/cm³
• Vapor Pressure: 1.78E-14mmHg at 25°C
• Refractive Index: 1.674
• CAS DataBase Reference: (3E,6E)-3-but-2-en-1-ylidene-6-(phenylmethylidene)piperazine-2,5-dione(CAS DataBase Reference)
• NIST Chemistry Reference: (3E,6E)-3-but-2-en-1-ylidene-6-(phenylmethylidene)piperazine-2,5-dione(51245-20-6)
• EPA Substance Registry System: (3E,6E)-3-but-2-en-1-ylidene-6-(phenylmethylidene)piperazine-2,5-dione(51245-20-6)

Safety Data

• Hazardous Substances Data: 51245-20-6(Hazardous Substances Data)

Usage

General Description

The chemical compound (3E,6E)-3-but-2-en-1-ylidene-6-(phenylmethylidene)piperazine-2,5-dione, also known as SU6668, is a synthetic organic molecule with potential antiangiogenic and antineoplastic activities. It is a small molecule inhibitor that targets receptor tyrosine kinases, in particular the vascular endothelial growth factor (VEGF) receptor and the fibroblast growth factor (FGF) receptor, which are involved in tumor angiogenesis and growth. SU6668 has been studied for its potential use in cancer therapy, particularly as a treatment for solid tumors. It has shown promising results in preclinical studies, demonstrating inhibitory effects on angiogenesis and tumor growth. However, further research is needed to evaluate its safety and efficacy in clinical settings.