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51247-07-5

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51247-07-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 51247-07-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,2,4 and 7 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 51247-07:
(7*5)+(6*1)+(5*2)+(4*4)+(3*7)+(2*0)+(1*7)=95
95 % 10 = 5
So 51247-07-5 is a valid CAS Registry Number.

51247-07-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name [(2R,3S,5R)-3-fluoro-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl acetate

1.2 Other means of identification

Product number -
Other names 5'-O-acetyl-FLT

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:51247-07-5 SDS

51247-07-5Upstream product

51247-07-5Downstream Products

51247-07-5Relevant academic research and scientific papers

The potential of aspirin in prodrug synthesis: A new potential delivery system of AZT and FLT

Zahran, Magdy A.,Kovacs, Lajos,El Sakka, Ibrahim,Pedersen, Erik B.,Nielsen, Claus

, p. 417 - 420 (1996)

Aspirin (O-acetylsalicylic acid) has been used to synthesize prodrugs of 3'-azido-3'-deoxythymidine (AZT) and 3'-deoxy-3'-fluorothymidine (FLT). The mixed anhydride between aspirin and trifluoroacetic acid was synthesized and reacted with AZT and FLT to give the blocked nucleosides attached through the 5'-O position to the 2-position of 2-methyl-4H-1,3-benzodioxin-4-one. The prodrugs showed the same activities against HIV-1 in MT-4 cells as the original drugs. Hydrolysis of the synthesized prodrugs in the growth medium, used for anti-HIV investigations, resulted in formation of 5-O acetylated drugs which were subsequently hydrolyzed into the original drugs.

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