51264-59-6

Basic information

• Product Name: 4-HYDROXY-2'-NITROBIPHENYL
• Synonyms: 2'-NITROBIPHENYL-4-OL;4-(2-NITROPHENYL)PHENOL;4-HYDROXY-2'-NITROBIPHENYL;Hydroxynitrobiphenyl;4-HYDROXY-2''-NITROBIPHENYL 97+%;2'-Nitro-1,1'-biphenyl-4-ol;2'-Nitrobiphenyl-4-ol 4-(2-Nitrophenyl)phenol;3-Nitro-4-phenylphenol
• CAS NO: 51264-59-6
• Molecular Formula: C₁₂H₉NO₃
• Molecular Weight: 215.2
• Mol File: 51264-59-6.mol
• Article Data: 3

Chemical Properties

• Melting Point: 115 °C
• Boiling Point: 371.547oC at 760 mmHg
• Flash Point: 161.106oC
• Appearance: /
• Density: 1.304g/cm3
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.638
• CAS DataBase Reference: 4-HYDROXY-2'-NITROBIPHENYL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-HYDROXY-2'-NITROBIPHENYL(51264-59-6)
• EPA Substance Registry System: 4-HYDROXY-2'-NITROBIPHENYL(51264-59-6)

Safety Data

• Hazardous Substances Data: 51264-59-6(Hazardous Substances Data)

Usage

General Description

4-Hydroxy-2'-nitrobiphenyl, also known as 2-nitro-4-phenylphenol, is a chemical compound with the molecular formula C12H9NO3. It falls under the category of organooxygen compounds, particularly the class of nitrobiphenyls. Its structure includes two benzene rings linked by a single bond, also known as a biphenyl structure, with a nitro group (NO2) and a hydroxy group (OH) attached. The positioning of these groups gives the compound its '4-hydroxy-2'-nitro' designation. 4-HYDROXY-2'-NITROBIPHENYL is a solid substance at room temperature and is used in a variety of scientific research and industrial applications.

InChI:InChI=1/C12H9NO3/c14-10-7-5-9(6-8-10)11-3-1-2-4-12(11)13(15)16/h1-8,14H

Upstream product

• 113305-56-9 4-iodo-3-nitrophenol 
• 98-80-6 phenylboronic acid 
• 2170-13-0 biphenyl 4-yl benzoate 
• 5344-78-5 4-bromo-3-nitroanizole 
• 16098-16-1 4-methoxy-2-nitro-1,1'-biphenyl 

Downstream Products

• 86-79-3 2-hydroxycarbazole 

Relevant articles and documents

NEW CYCLOHEXYL AND QUINUCLIDINYL CARBAMATE DERIVATIVES HAVING BETA2 ADRENERGIC AGONIST AND M3 MUSCARINIC ANTAGONIST ACTIVITY

The present invention relates to novel compounds having β2 adrenergic agonist and M3 muscarinic antagonist dual activity, to pharmaceutical compositions containing them, to the process for their preparation and to their use in respiratory therapies.

Triphenylphosphine-mediated reductive cyclization of 2-nitrobiphenyls: A practical and convenient synthesis of carbazoles

The synthesis of a series of substituted carbazoles from the corresponding 2-nitrobiphenyl derivatives using a novel modification of the Cadogan reaction is described. Cyclization of the 2-nitrobiphenyls was achieved via reductive deoxygenation of the nitro groups using a slight excess of triphenylphosphine in a suitable solvent. We have observed a temperature dependence on the extent of conversion under these conditions, with higher boiling solvents affording higher yields across a range of substrates. The new reaction conditions are very straightforward and convenient to execute, tolerate a broad range of functional groups, and yield carbazole products in the absence of unwanted side products.