512789-12-7Relevant articles and documents
Application of iridium catalyzed allylic substitution reactions in the synthesis of branched tryptamines and homologues via tandem hydroformylation- Fischer indole synthesis
Bondzic, Bojan P.,Farwick, Andreas,Liebich, Jens,Eilbracht, Peter
supporting information; experimental part, p. 3723 - 3731 (2009/02/05)
Combination of enantioselective allylation reactions with a tandem hydroformylation-Fischer indole synthesis sequence as a highly diversity-oriented strategy for the synthesis of tryptamines and homologues was explored. This modular approach allows the su
Enantioselective allylation of aromatic amines after in situ generation of an activated cyclometalated iridium catalyst
Shu, Chutian,Leitner, Andreas,Hartwig, John F.
, p. 4797 - 4800 (2007/10/03)
Highly regio- and enantioselective allylation of aromatic amines is observed when a cyclometalated Ir-phosphoramidite complex is generated in situ (see scheme). The active catalyst can be formed from [{Ir(cod)Cl}2] and ligand L with a volatile alkylamine prior to addition of the reagents or upon use of a tertiary amine additive.