512797-28-3

Basic information

• Product Name: Urea, N-(4,5-dihydro-2-phenyl-4-oxazolyl)-N'-phenyl-N-(phenylmethyl)-
• CAS NO: 512797-28-3
• Molecular Formula: C23H21N3O2
• Molecular Weight: 371.439
• Mol File: 512797-28-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Urea, N-(4,5-dihydro-2-phenyl-4-oxazolyl)-N'-phenyl-N-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Urea, N-(4,5-dihydro-2-phenyl-4-oxazolyl)-N'-phenyl-N-(phenylmethyl)-(512797-28-3)
• EPA Substance Registry System: Urea, N-(4,5-dihydro-2-phenyl-4-oxazolyl)-N'-phenyl-N-(phenylmethyl)-(512797-28-3)

Safety Data

• Hazardous Substances Data: 512797-28-3(Hazardous Substances Data)

Upstream product

• 473724-11-7 N-(1-benzylamino-2,2-dichloroethyl)-2-chlorobenzamide 
• 130775-03-0 N-(1-benzylamino-2,2-dichloroethyl)benzamide 
• 103-71-9 phenyl isocyanate 
• 203444-38-6 4-benzylamino-2-phenyl-2-oxazoline 

Relevant articles and documents

The reaction of 4-amino-2-oxazolines with isocyanates and isothiocyanates. Synthesis and X-ray structures of polysubstituted 2-imidazolidinones, 1,3-oxazolidines and 1,3-thiazolidines

Reactions of 4-alkylamino-2-phenyl-2-oxazolines 1 with isocyanates and isothiocyanates provide unprecedented efficient and regioselective heterocycle-heterocycle transformations. Compounds 1 reacted rapidly with tosyl isocyanate yielding directly 3-alkyl-

Electrochemical generation of 4-amino-2-aryl-2-oxazolines

A convenient method for the synthesis of the title compounds has been established. Chloralbenzamides were efficiently converted to N-(1-amino-2,2-dichloroethyl)benzamides which were directly transformed to 4-amino-2-aryl-2-oxazolines in fair to good yields by electrochemical reduction in an aprotic medium under constant cathodic potential. The molecular structure of the electrolysis products has been corroborated by X-ray crystallographic analysis of 4-(1-benzyl-3-phenylureido)-2-phenyl-2-oxazoline.