512847-61-9

Basic information

• Product Name: [4-(2-chloro-4-trifluoromethyl-phenyl)-3-nitro-pyridin-2-yl]-(1-methoxymethyl-propyl)-amine
• CAS NO: 512847-61-9
• Molecular Weight: 403.788
• Mol File: 512847-61-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [4-(2-chloro-4-trifluoromethyl-phenyl)-3-nitro-pyridin-2-yl]-(1-methoxymethyl-propyl)-amine(CAS DataBase Reference)
• NIST Chemistry Reference: [4-(2-chloro-4-trifluoromethyl-phenyl)-3-nitro-pyridin-2-yl]-(1-methoxymethyl-propyl)-amine(512847-61-9)
• EPA Substance Registry System: [4-(2-chloro-4-trifluoromethyl-phenyl)-3-nitro-pyridin-2-yl]-(1-methoxymethyl-propyl)-amine(512847-61-9)

Safety Data

• Hazardous Substances Data: 512847-61-9(Hazardous Substances Data)

Upstream product

• 63448-63-5 2-amino-1-methoxybutane 
• 512847-47-1 2-benzyloxy-4-(2-chloro-4-trifluoromethyl-phenyl)-3-nitro-pyridine 
• 677743-25-8 4-(2-chloro-4-trifluoromethyl-phenyl)-3-nitro-pyridin-2-ol 
• 219735-84-9 2-benzyloxy-4-chloro-3-nitropyridine 
• 165547-79-5 2-hydroxy-3-nitro-4-chloropyridine 

Relevant articles and documents

Imidazo[4,5-b]pyridines as corticotropin releasing factor receptor ligands.

A series of high affinity CRF receptor ligands with an imidazo[4,5-b]pyridine core is described. Individual analogues were synthesized and tested in a rat CRF receptor binding assay. The best compounds were further tested in the dog N-in-1 pharmacokinetic model to assess plasma levels at 1mg/kg (po) and in the rat situational anxiety model to assess anxiolytic efficacy at 3mg/kg (po). The structure-activity relationships for good receptor binding affinity are described herein.