51296-11-8Relevant articles and documents
Oxidation products of phenolic thiocolchicines: Ring a quinones and dienones
Guan, Jian,Brossi, Arnold,Zhu, Xiao-Kang,Wang, Hui-Kang,Lee, Kuo-Hsiung
, p. 1585 - 1591 (1998)
An improved, highly selective demethylation of thiocolchicine (1) to the diphenol 5 is described. Oxidation of 2 to para-quinone 6 and of 4 and 5 to ortho-quinones 8 and 10 is first reported. Also, 2-demethylthiocolchicine (3) was oxidized to the quinone methide 7.