513-42-8Relevant articles and documents
Tailoring Polyethers for Post-polymerization Functionalization by Cross Metathesis
Morrison, Stephen D.,Liskamp, Rob M. J.,Prunet, Jo?lle
, p. 2253 - 2256 (2018)
Olefin cross metathesis is reported for the first time to attach small molecules to a range of novel polyethers with a poly(ethylene glycol) backbone and pendent alkene groups, allowing for a loading of up to one compound per monomer unit. These polymers are tailored to prevent the occurrence of self metathesis (reaction of the polymer with itself) by varying the substitution on the pendent alkenes, thus steering their reactivity toward olefin cross metathesis. Efficient functionalization has been observed for a range of coupling partners as a proof of concept for the use of olefin metathesis to graft small and larger molecules to polyethers for drug delivery. This approach also paves the way for the use of olefin cross metathesis as an efficient method to functionalize a wide variety of polymers with pendent olefin groups.
Scheschukow
, (1884)
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Currell,Fry
, p. 4377 (1956)
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METHOD FOR PREPARING 2-METHALLYL ALCOHOL
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Paragraph 0036-0053, (2021/06/09)
2 - Allyl chloride is reacted in the presence of a catalyst in a basic aqueous solution. The catalyst is an ionic liquid (Ionic liquid) and relates to a method for producing 2 -methallyl alcohol. To the present invention, 2 - metaallyl alcohol having high selectivity and high yield can be provided.
METHOD FOR SEPARATING AND PREPARING 2-METHALLYL ALCOHOL
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Paragraph 0038-0053, (2021/06/09)
The reaction of 2 -methallyl chloride with a basic aqueous solution to produce a 1-phase reaction solution (Step 1). 1: The reaction solution 2 is prepared by adding an aqueous alkali metal salt solution or an alkaline earth metal salt aqueous solution to the reaction solution to produce an agent 2. The method 2 according to claim 3, wherein the reaction mixture is separated into a water layer and an oil layer. The 2 -methallyl alcohol according to claim 4, wherein 2 -allyl alcohol is separated from the oil layer. To the present invention, 2 - metaallyl alcohol can be separated and recovered at a high recovery rate.