51318-98-0

Usage

Uses

Used in Pharmaceutical Industry:
2-(carboxymethyl)bicyclo[2.2.1]hept-5-ene-2-carboxylic acid is used as a pharmaceutical compound for its potential to impart unique properties to drug molecules. Its bicyclic structure and functional groups can enhance the efficacy and selectivity of drugs, making it a valuable component in the development of new medications.
Used in Organic Synthesis:
2-(carboxymethyl)bicyclo[2.2.1]hept-5-ene-2-carboxylic acid serves as a building block in organic synthesis, allowing for the creation of a wide range of specialty chemicals. Its versatile structure and functional groups enable the synthesis of various complex molecules, contributing to the advancement of chemical research and development.
Used in Material Science:
2-(carboxymethyl)bicyclo[2.2.1]hept-5-ene-2-carboxylic acid has the potential to be used in the development of new materials and polymers. Its unique structure and functional groups can be utilized to create innovative materials with specific properties, such as improved strength, flexibility, or chemical resistance, for various applications in industries like aerospace, automotive, and electronics.

Upstream product

• 97-65-4 2-methylenesuccinic acid 
• 542-92-7 cyclopenta-1,3-diene 
• 2170-03-8 itaconic acid anhydride 
• 58601-47-1 (+/-)-(2exo-carboxy-norborn-5-ene-2endo-yl)-acetic acid-anhydride 

Relevant academic research and scientific papers

Functional norbornanyl ester derivatives, polymers and process for preparing same

This invention relates to the new functional norbornanyl ester derivative and/or polymer compositions which are easily obtainable by reacting the Diels-Alder adduct of appropriate dienes and dienophiles with carboxylic acids. In particular, this invention relates to a new process for making cyclic chemical raw materials suitable for production coating, ink, adhesive, plasticizer, thermoplastic or thermosetting plastic and functional polymers.

A direct route to angularly substituted hydrindanes. Formal synthesis of bakkenolide-A and synthesis of an advanced intermediate to umbellactal

A direct route for the synthesis of highly functionalized angularly substituted hydrindanes has been developed. The key step involves RO-RCM of an appropriately functionalized norbornene derivative. The hydrindane derivative obtained in this way has been

Cyclopentanedi- and tricarboxylic acids as squalene synthase inhibitors: Syntheses and evaluation

Based on earlier lead squalene synthase inhibitor A-87049 (3) and zaragozic acids, a series of cyclopentanedi- and tricarboxylic acids were synthesized and evaluated against the enzyme. Some exhibited good potency and SAR revealed the importance of conformation and substitution pattern of these synthetic inhibitors.

Strategic use of retro Diels-Alder reaction in the construction of β-carboxy-α-methylene-γ-lactones. Total synthesis of methylenolactocin and protolichesterinic acid

A facile route for the construction of β-carboxy-α-methylene-γ-lactone unit is described using retro Diels-Alder reaction as the key step. Using this protocol, total synthesis of (±)-methylenolactocin and (±)-protolichesterinic acid has been achieved.

Heterocyclic spiro compounds

Compounds of the class of spiro[norbornane-2,3'-piperidines], spiro[bicyclo[2.2.2]octane-2,3'-piperidines], and corresponding spiro-pyrrolidine derivatives which are unsubstituted at the ring nitrogen atom or substituted by neutral or basic radicals, and