H-Gln-O-But, also known as tert-butyloxycarbonyl-glutamine, is a chemical compound that serves as a protecting group in peptide synthesis. It is a derivative of glutamine, an amino acid, where the side chain amide group is protected by a tert-butyloxycarbonyl (Boc) group. This protection is crucial for preventing unwanted side reactions during the synthesis of peptides, particularly when using the Boc-SPPS (solid-phase peptide synthesis) method. The Boc group can be selectively removed under mild acidic conditions, allowing for the subsequent coupling of the next amino acid in the peptide chain. H-Gln-O-But is a key component in the stepwise assembly of peptides, ensuring that the glutamine residue is incorporated correctly and without premature reactivity.
The CAS Registry Mumber 5132-46-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,1,3 and 2 respectively; the second part has 2 digits, 4 and 6 respectively. Calculate Digit Verification of CAS Registry Number 5132-46: (6*5)+(5*1)+(4*3)+(3*2)+(2*4)+(1*6)=67 67 % 10 = 7 So 5132-46-7 is a valid CAS Registry Number.