51333-75-6 Usage
Uses
Used in Organic Synthesis:
2-(Methylthio)phenyl isothiocyanate is used as a reagent in organic synthesis for its ability to form a variety of chemical compounds, contributing to the development of new materials and products.
Used in Biochemical Research:
In biochemical research, 2-MTPITC serves as a valuable tool for studying various biological processes and mechanisms, given its reactivity and potential to interact with biomolecules.
Used in Pharmaceutical Compounds:
2-(Methylthio)phenyl isothiocyanate is used as a reactive intermediate in the synthesis of pharmaceutical compounds, leveraging its chemical properties to create new drugs with potential therapeutic applications.
Used in Agrochemicals:
2-(METHYLTHIO)PHENYL ISOTHIOCYANATE is also utilized in the development of agrochemicals, where its potential antimicrobial and antifungal properties can be harnessed to protect crops and enhance agricultural productivity.
Used in Environmental Protection:
Although 2-MTPITC has potential environmental hazards, it is also studied for its role in environmental protection, such as in the development of compounds that can combat harmful microorganisms in various settings.
Used in Material Science:
In material science, 2-MTPITC may be employed to create new materials with specific properties, such as those with enhanced antimicrobial capabilities for use in various industries, including healthcare and manufacturing.
Check Digit Verification of cas no
The CAS Registry Mumber 51333-75-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,3,3 and 3 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 51333-75:
(7*5)+(6*1)+(5*3)+(4*3)+(3*3)+(2*7)+(1*5)=96
96 % 10 = 6
So 51333-75-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H7NS2/c1-11-8-5-3-2-4-7(8)9-6-10/h2-5H,1H3
51333-75-6Relevant academic research and scientific papers
Differentiating Antiproliferative and Chemopreventive Modes of Activity for Electron-Deficient Aryl Isothiocyanates against Human MCF-7 Cells
Anderson, Ruthellen H.,Lensing, Cody J.,Forred, Benjamin J.,Amolins, Michael W.,Aegerter, Cassandra L.,Vitiello, Peter F.,Mays, Jared R.
, p. 1695 - 1710 (2018/08/01)
The consumption of Brassica vegetables provides beneficial effects through organic isothiocyanates (ITCs), products of the enzymatic hydrolysis of glucosinolate secondary metabolites. The ITC l-sulforaphane (l-SFN) is the principle agent in broccoli that demonstrates several modes of anticancer action. While the anticancer properties of ITCs like l-SFN have been extensively studied and l-SFN has been the subject of multiple human clinical trials, the scope of this work has largely been limited to those derivatives found in nature. Previous studies have demonstrated that structural changes in an ITC can lead to marked differences in a compound's potency to 1) inhibit the growth of cancer cells, and 2) alter cellular transcriptional profiles. This study describes the preparation of a library of non-natural aryl ITCs and the development of a bifurcated screening approach to evaluate the dose- and time-dependence on antiproliferative and chemopreventive properties against human MCF-7 breast cancer cells. Antiproliferative effects were evaluated using a commercial MTS cell viability assay. Chemopreventive properties were evaluated using an antioxidant response element (ARE)-promoted luciferase reporter assay. The results of this study have led to the identification of 1) several key structure–activity relationships and 2) lead ITCs for continued development.
