51336-32-4

Basic information

• Product Name: 2,6-Dimethyl-4-[4-(2-ethoxycarbonylprop-2-oxy)phenyl]-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester
• Synonyms: 2,6-Dimethyl-4-[4-(2-ethoxycarbonylprop-2-oxy)phenyl]-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester
• CAS NO: 51336-32-4
• Molecular Weight: 459.54
• Mol File: 51336-32-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,6-Dimethyl-4-[4-(2-ethoxycarbonylprop-2-oxy)phenyl]-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-Dimethyl-4-[4-(2-ethoxycarbonylprop-2-oxy)phenyl]-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester(51336-32-4)
• EPA Substance Registry System: 2,6-Dimethyl-4-[4-(2-ethoxycarbonylprop-2-oxy)phenyl]-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester(51336-32-4)

Safety Data

• Hazardous Substances Data: 51336-32-4(Hazardous Substances Data)

Upstream product

• 600-00-0 ethyl 2-bromoisobutyrate 
• 10354-30-0 4-(4-hydroxy-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester 

Relevant articles and documents

1,4-Dihydropyridines

Derivatives of 4-substituted phenyl 1,4-dihydropyridine 3,5-dicarboxylic acids substituted by lower alkyl groups in the 2- and 6-positions, are cardiovascular agents. The compounds, of which 2,6-dimethyl-4-[2-(diethylaminoethoxy)-phenyl]-1,4-dihydropyridine-3,5-dicarboxylic acid 3,5-diethyl ester is a typical example, can be prepared through condensation of a β-dicarbonyl compound with an amine and an aldehyde, of an ylidene-β-ketocarboxylic acid ester, with a β-ketocarbonyl compound and an amine, of an aldehyde, an enamine and a β-ketocarbonyl compound, or through elaboration of the substituent on the phenyl group.