51360-00-0

Basic information

• Product Name: N,N-Dimethylspiro[5H-dibenzo[a,d]cycloheptene-5,1'-cyclopentan]-3'-amine
• Synonyms: N,N-Dimethylspiro[5H-dibenzo[a,d]cycloheptene-5,1'-cyclopentan]-3'-amine
• CAS NO: 51360-00-0
• Molecular Formula: C21H23N
• Molecular Weight: 289.41
• Mol File: 51360-00-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 431.7±44.0 °C(Predicted)
• Appearance: /
• Density: 1.11±0.1 g/cm3(Predicted)
• PKA: 10.81±0.20(Predicted)
• CAS DataBase Reference: N,N-Dimethylspiro[5H-dibenzo[a,d]cycloheptene-5,1'-cyclopentan]-3'-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-Dimethylspiro[5H-dibenzo[a,d]cycloheptene-5,1'-cyclopentan]-3'-amine(51360-00-0)
• EPA Substance Registry System: N,N-Dimethylspiro[5H-dibenzo[a,d]cycloheptene-5,1'-cyclopentan]-3'-amine(51360-00-0)

Safety Data

• Hazardous Substances Data: 51360-00-0(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 

Relevant articles and documents

Antidepressant agents. I. Chemistry and pharmacology of amino substituted spiro[5H dibenzo[a,d]cycloheptene 5,1' cycloalkanes]

A series of spiro compounds structurally related to the common tricyclic antidepressants has been tested as inhibitors of the neuronal reuptake of noradrenaline and 5 hydroxytryptamine. Also, some behavioral tests have been performed. Two of the substances, N,N dimethylspiro [5H dibenzo[a,d]cycloheptene 5,1' cyclohex 2' en] 4' amine and N,N dimethylspiro [5H dibenzo[a,d]cycloheptene 5,1' cyclohexan] 4' amine, are very active in the NA uptake inhibition assay. A discussion on structure activity relationships is given.