5137-52-0Relevant academic research and scientific papers
Palladium-Catalyzed Decarboxylative Carbonylative Transformation of Benzyl Aryl Carbonates: Direct Synthesis of Aryl 2-Arylacetates
Xu, Jian-Xing,Wu, Xiao-Feng
, p. 5938 - 5941 (2018/09/21)
A procedure on palladium-catalyzed decarboxylative alkoxycarbonylation of carbonates for the synthesis of aryl 2-arylacetates has been developed. A broad range of aryl 2-arylacetates were obtained in good yields under mild conditions under a carbon monoxide atmosphere. Interestingly, other alcohols can be added as nucleophiles as well, and the corresponding esters were also obtained in good yields.
Carboxyl activation of 2-mercapto-4,6-dimethylpyrimidine through n-acyl-4,6-dimethylpyrimidine-2-thione: A chemical and spectrophotometric investigation
Rajan
, p. 287 - 291 (2015/01/30)
2-Mercapto-4,6-dimethylpyrimidine, as effective carboxyl activating group, has been successfully proved by converting it into respective acyl derivatives and the subsequent conversion to the amides and esters respectively using amines, amino alcohols and alcohols. The aminolysis and esterification were monitored chemically and spectrophotometrically. This paved way to establish that the above mercaptopyrimidine derivative is an efficient carboxyl activating group applicable in solid phase peptide synthesis.
Carboxyl activation of 3-mercapto-5,6-diphenyl-1,2,4-triazine through N-phenylacetyl-5,6-diphenyl-1,2,4-triazine-3-thione
Rajan
, p. 119 - 126 (2019/01/21)
The carboxyl activation ability of 3-mercapto-5,6-diphenyl-1,2,4-triazine has been established by coverting it into N-phenylacetyl-5,6-diphenyl-1,2,4-triazine-3-thione and this was then subjected to aminolysis and esterification with amines and alcohols respectively and selective aminolysis with aminoalcohols-monitoring chemically and confirmed spectrophotometrically by UV-Visible scannings. It could be proved that 3- mercapto-5,6-diphenyl-1,2,4-triazine is an efficient carboxyl activating group which can be successfully applied in solid phase peptide synthesis.
Copper-catalyzed highly efficient ester formation from carboxylic acids/esters and formates
Liu, Jun,Shao, Changdong,Zhang, Yanghui,Shi, Guangfa,Pan, Shulei
supporting information, p. 2637 - 2640 (2014/05/06)
A highly efficient copper-catalyzed protocol for the synthesis of esters has been developed from formates. This protocol is applicable to reactions with either esters or acids as the substrates, and shows broad substrate scopes and high yields. This journal is the Partner Organisations 2014.
A fast and simple method for the acylation of alcohols with acid chlorides promoted by metallic samarium
Jia, Xue-Shun,Wang, Hai-Long,Huang, Qing,Kong, Ling-Long,Zhang, Wei-He
, p. 135 - 138 (2007/10/03)
Acylation of primary, secondary, allyl and benzyl alcohols with acid chlorides promoted by samarium metal under neutral condition gave carboxylic acid esters in good to excellent yields. Acylation of a tertiary alcohol did not occur under the same reaction conditions.
Esterification of carboxylic acids with alcohols under microwave irradiation in the presence of zinc triflatet
Shekarriz, Marzieh,Taghipoor, Sohrab,Khalili, Ali Asghar,Jamarani, Mohammad Soleymani
, p. 172 - 173 (2007/10/03)
The esterification of aliphatic and aromatic carboxylic acids with various alcohols (1°, 2°, 3°, benzylic) was studied under microwave irradiation in the presence of zinc triflate as catalyst; the reaction times were short and the yield of reactions was good to excellent.
An efficient use of zeolite catalysts for esterification of carboxylic acids
Gumaste, Vikas K.,Deshmukh,Bhawal
, p. 1174 - 1179 (2007/10/03)
A mild and practical method (batch process) for the esterification of carboxylic acids with alcohols using zeolite catalysts in good to excellent yields is described. The esterification of phenylacetic acid with ethanol has also been carried out in very high yield using continuous flow fixed bed reactor.
Oxidation of Alkynes by Hydrogen Peroxide Catalyzed by Methylrhenium Trioxide
Zhu, Zuolin,Espenson, James H.
, p. 7728 - 7732 (2007/10/03)
The oxidation of alkynes with hydrogen peroxide is catalyzed by methylrhenium tioxide.The reactions can be rationalized by postulating that an oxirene intermediate is formed between a rhenium peroxide and the alkyne.Internal alkynes yield α-diketones and carboxylic acids, the latter from the complete cleavage of the triple bonds.Rearrangement products were observed only for aliphatic alkynes.Terminal alkynes gave carboxylic acids and their derivatives and α-keto acids as the major products, but their yields varied with the solvent used.
