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51387-68-9

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  • Guanidine, 1-[4-chloro-.alpha.,.alpha., .alpha.-trifluoro-m-tolyl]-3-[4-[[2-(diisopropylamino)ethyl]amino] -6-methyl-2-pyrimidinyl]-

    Cas No: 51387-68-9

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  • Guanidine, 1-[4-chloro-.alpha.,.alpha., .alpha.-trifluoro-m-tolyl]-3-[4-[[2-(diisopropylamino)ethyl]amino] -6-methyl-2-pyrimidinyl]- cas 51387-68-9

    Cas No: 51387-68-9

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51387-68-9 Usage

Chemical structure

A guanidine derivative with a complex structure that includes a 4-chloro-3-(trifluoromethyl)phenyl group, a 4-[2-(dipropan-2-ylamino)ethyl]amino-6-methylpyrimidin-2-yl group, and a guanidine functional group.

Target

TRPC6, a calcium-permeable cation channel that is implicated in the pathogenesis of various diseases.

Mechanism of action

By inhibiting TRPC6, the compound modulates calcium homeostasis and reduces pathological processes associated with TRPC6 overactivity.

Potential therapeutic applications

The compound has potential therapeutic applications in the treatment of various diseases, including kidney diseases and neurological disorders.

Further research needed

More research and clinical studies are required to fully evaluate the therapeutic potential of this compound in the treatment of various diseases.

Chemical class

Guanidine derivative.

Molecular target

TRPC6 calcium-permeable cation channel.

Mode of action

Inhibition of TRPC6 channel activity, leading to modulation of calcium homeostasis and reduction of pathological processes associated with TRPC6 overactivity.

Check Digit Verification of cas no

The CAS Registry Mumber 51387-68-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,3,8 and 7 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 51387-68:
(7*5)+(6*1)+(5*3)+(4*8)+(3*7)+(2*6)+(1*8)=129
129 % 10 = 9
So 51387-68-9 is a valid CAS Registry Number.

51387-68-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name Guanidine, 1-[4-chloro-.α.,.α.,.α.-trifluoro-m-tolyl]-3-[4-[[2-(diisopropylamino)ethyl]amino]-6-methyl-2-pyrimidinyl]-

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:51387-68-9 SDS

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