51390-23-9

Basic information

• Product Name: 1-(3-HYDROXYPROPYL)-1H-IMIDAZOLE
• Synonyms: CHEMBRDG-BB 4010926;1-(3-HYDROXYPROPYL)-1H-IMIDAZOLE;3-IMIDAZOL-1-YL-PROPAN-1-OL;1-(3-HYDROXYPROPYL)-1H-IMIDAZOLE >98%;3-(1H-imidazol-1-yl)propan-1-ol(SALTDATA: HCl);3-(1H-imidazol-1-yl)propan-1-ol 1HCl;3-(1H-imidazol-1-yl)propan-1-ol;3-(1-imidazolyl)propan-1-ol
• CAS NO: 51390-23-9
• Molecular Formula: C₆H₁₀N₂O
• Molecular Weight: 126.16
• Mol File: 51390-23-9.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 132°C/0.2mm
• Flash Point: 151.1 °C
• Appearance: /
• Density: 1.11 g/cm³
• Vapor Pressure: 8.85E-05mmHg at 25°C
• Refractive Index: 1.54
• Storage Temp.: 2-8°C
• PKA: 14.66±0.10(Predicted)
• CAS DataBase Reference: 1-(3-HYDROXYPROPYL)-1H-IMIDAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-HYDROXYPROPYL)-1H-IMIDAZOLE(51390-23-9)
• EPA Substance Registry System: 1-(3-HYDROXYPROPYL)-1H-IMIDAZOLE(51390-23-9)

Safety Data

• Hazardous Substances Data: 51390-23-9(Hazardous Substances Data)

Usage

General Description

1-(3-Hydroxypropyl)-1H-imidazole is a chemical compound that belongs to the class of imidazole derivatives. It is a white crystalline solid with a molecular formula C6H10N2O and a molecular weight of 126.154 g/mol. 1-(3-HYDROXYPROPYL)-1H-IMIDAZOLE is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is also employed in the production of water-soluble polymers and as a corrosion inhibitor for metal surfaces. Additionally, 1-(3-Hydroxypropyl)-1H-imidazole has potential applications in the fields of biochemistry and molecular biology due to its ability to interact with biological molecules such as proteins and nucleic acids. However, it is important to handle this chemical with care and follow proper safety precautions due to its potential hazards.

InChI:InChI=1/C6H10N2O/c9-5-1-3-8-4-2-7-6-8/h2,4,6,9H,1,3,5H2

Upstream product

• 288-32-4 1H-imidazole 
• 2453-03-4 trimethylene carbonate 
• 627-18-9 1-bromo-3-propanol 
• 627-30-5 1-chloro-3-hydroxypropane 
• 18999-46-7 methyl 3-(imidazol-1-yl)propionate 
• 24215-02-9 3-imidazol-1-yl-propionic acid ethyl ester 
• 616236-63-6 Acetic acid 3-imidazol-1-yl-propyl ester 

Downstream Products

• 198961-85-2 4-[N-(3-bromophenyl)amino]-7-[3-(1H-imidazol-1-yl)propoxy]-6-nitroquinazoline 
• 1292805-17-4 C₂₁H₂₃N₃O₄S 
• 1284038-61-4 C₁₄H₁₆N₂O₃ 
• 1313902-01-0 C₁₅H₁₈N₂O₃ 
• 198961-86-3 6-amino-4-[N-(3-bromophenyl)amino]-7-[3-(1H-imidazol-1-yl)propoxy]quinazoline 
• 220363-49-5 4-[3-(3-imidazol-1-yl-propyl)-5-methyl-5-naphthalen-1-yl-2,4-dioxo-imidazolidin-1-ylmethyl]-benzoic acid 
• 220363-44-0 1-(4-aminomethyl-benzyl)-3-(3-imidazol-1-yl-propyl)-5-methyl-5-naphthalen-1-yl-imidazolidin-2,4-dione 

Relevant articles and documents

N-Alkylation of Imidazoles with Dialkyl and Alkylene Carbonates

Abstract: The reactions of imidazoles with a series of dialkyl and alkylene carbonatesafforded the corresponding N-alkyl- andN-(hydroxyalkyl)imidazoles with highyields. The reactivity of dialkyl carbonates decreases in the series dimethyl> diethyl > dibutyl carbonate. Ethylene carbonate is a more efficientalkylating agent than trimethylene carbonate. The mechanisms of alkylation ofimidazole with dimethyl carbonate and ethylene carbonate were studied by DFTquantum chemical calculations at the B3LYP/6-311++G(d,p) level of theory.

FLAVIN DERIVATIVES

The present invention relates novel flavin derivatives and other flavin derivatives, their use and compositions for use as riboswitch ligands and/or anti-infectives. The invention also provides method of making novel flavin derivatives.

AGENT FOR IMPROVING PERMEATION OF A DRUG INTO A NAIL AND AN EXTERNAL TREATING AGENT CONTAINING THE SAME

The present invention herein provides a compound which promotes drug-permeation into nails. A penetrating promoter comprises, for instance, the following formulas. R1, R2 and R3 are alkyl groups having a carbon number of 1 to 15 and have OH groups at their ends.