16-Methylepihydrocortisone is a synthetic corticosteroid derived from hydrocortisone, which is a naturally occurring hormone produced by the adrenal glands. It is characterized by the presence of a methyl group at the 16th carbon position, which enhances its anti-inflammatory and immunosuppressive properties. This modification makes 16-Methylepihydrocortisone more potent than its parent compound, hydrocortisone, and it is used in the treatment of various inflammatory and autoimmune conditions, such as rheumatoid arthritis, lupus, and severe asthma. The chemical structure of 16-Methylepihydrocortisone allows it to bind more effectively to glucocorticoid receptors, thereby increasing its therapeutic efficacy. It is typically administered in the form of tablets, injections, or creams, and its use is closely monitored by healthcare professionals due to potential side effects and the need for careful dosage adjustments.

514-55-6

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Basic information
1. Product Name: 16-Methylepihydrocortisone
2. Synonyms: 11,17,21-Trihydroxy-16-methylpregn-4-ene-3,20-dione;16-Methylepihydrocortisone;16-Methylpregn-4-ene-11,17,21-triol-3,20-dione
3. CAS NO:514-55-6
4. Molecular Formula: C22H32O5
5. Molecular Weight: 376.49
6. EINECS: N/A
7. Product Categories: N/A
8. Mol File: 514-55-6.mol
Chemical Properties
1. Melting Point: N/A
2. Boiling Point: N/A
3. Flash Point: N/A
4. Appearance: /
5. Density: N/A
6. Refractive Index: N/A
7. Storage Temp.: N/A
8. Solubility: N/A
9. CAS DataBase Reference: 16-Methylepihydrocortisone(CAS DataBase Reference)
10. NIST Chemistry Reference: 16-Methylepihydrocortisone(514-55-6)
11. EPA Substance Registry System: 16-Methylepihydrocortisone(514-55-6)
Safety Data
1. Hazard Codes: N/A
2. Statements: N/A
3. Safety Statements: N/A
4. WGK Germany:
5. RTECS:
6. HazardClass: N/A
7. PackingGroup: N/A
8. Hazardous Substances Data: 514-55-6(Hazardous Substances Data)

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514-55-6 Usage

Type of compound

Synthetic glucocorticoid steroid

Structural similarity

Naturally occurring hormone cortisol

Properties

Anti-inflammatory and immunosuppressive

Uses

Treatment of allergic reactions, asthma, and autoimmune diseases

Mechanism of action

Binds to glucocorticoid receptors, modulating gene expression in immune response and inflammatory processes

Available forms

Oral tablets, injections, and topical creams

Prescription

By healthcare professionals for specific medical conditions

Side effects and risks

Potential side effects and risks associated with use

Supervision

Should only be used under the supervision of a healthcare provider

Check Digit Verification of cas no

The CAS Registry Mumber 514-55-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,1 and 4 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 514-55:
(5*5)+(4*1)+(3*4)+(2*5)+(1*5)=56
56 % 10 = 6
So 514-55-6 is a valid CAS Registry Number.

514-55-6Upstream product

1610-53-3 16α-Methyl-Δ⁴-pregnendiol-(17.21)-dion-(3.20)

514-55-6Downstream Products

514-55-6Relevant academic research and scientific papers

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