51409-75-7Relevant academic research and scientific papers
Ionic liquid promoted synthesis of β-enamino ketones at room temperature
Bhosale, Rajesh S.,Suryawanshi, Padmakar A.,Ingle, Sachin A.,Lokhande, Mahendra N.,More, Sandeep P.,Mane, Sandeep B.,Bhosale, Sidthanath V.,Pawar, Rajendra P.
, p. 933 - 935 (2006)
β-Enamino ketones have been synthesised in excellent yield at room temperature in the absence of any added catalyst by the reaction of aromatic or aliphatic amines with 1,3-dicarbonyl compounds in ionic liquid. The ionic liquid is recycled and reused several times. Georg Thieme Verlag Stuttgart.
Photocyclization to cis-Hexahydrocarbazol-4-ones: Substrate Modification, Mechanism, and Scope
Modha, Sachin G.,P?thig, Alexander,Dreuw, Andreas,Bach, Thorsten
, p. 1139 - 1153 (2019/01/30)
Upon irradiation at = 366 nm, tertiary N-alkoxycarbonyl-N-aryl-β-enaminones furnished exclusively the trans-hexahydrocarbazol-4-ones by a conrotatory [6π] photocyclization but epimerized on silica to cis-hexahydrocarbazol-4-ones (14 examples, 44-98% yield). The acceptor substitution on the nitrogen atom enhanced the stability of the cyclized products compared to N-alkyl-N-aryl-β-enaminones reported previously. The mechanism of the [6π] photocyclization was investigated by quenching experiments, deuterium-labeling experiments, and DFT calculations, suggesting a triplet pathway for the conrotatory ring closure followed by a suprafacial [1,4] hydrogen migration.
Synthesis, characterization and pharmacological screening of some novel 5-imidazopyrazole incorporated polyhydroquinoline derivatives
Kalaria, Piyush N.,Satasia, Shailesh P.,Raval, Dipak K.
, p. 207 - 216 (2014/04/17)
A new category of polyhydroquinoline derivatives 8a-t were synthesized in moderate to good yield (64-85%) by one-pot three-component cyclocondensation reaction of 5-(1H-imidazol-1-yl)-3-methyl-1-phenyl-1H-pyrazole-4-carbaldehyde 3 with various enaminones
