51409-83-7

Basic information

• Product Name: 3-[(2-chlorophenyl)amino]cyclohex-2-en-1-one
• Synonyms: 2-cyclohexen-1-one, 3-[(2-chlorophenyl)amino]-
• CAS NO: 51409-83-7
• Molecular Formula: C₁₂H₁₂ClNO
• Molecular Weight: 221.6828
• Mol File: 51409-83-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 348.6°C at 760 mmHg
• Flash Point: 164.6°C
• Density: 1.295g/cm³
• Vapor Pressure: 4.97E-05mmHg at 25°C
• Refractive Index: 1.638
• CAS DataBase Reference: 3-[(2-chlorophenyl)amino]cyclohex-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[(2-chlorophenyl)amino]cyclohex-2-en-1-one(51409-83-7)
• EPA Substance Registry System: 3-[(2-chlorophenyl)amino]cyclohex-2-en-1-one(51409-83-7)

Safety Data

• Hazardous Substances Data: 51409-83-7(Hazardous Substances Data)

Upstream product

• 504-02-9 1,3-cylohexanedione 
• 95-51-2 o-chloroaniline 

Downstream Products

• 1448015-47-1 5-amino-7-(2-chlorophenyl)-11-oxo-2,3,3a,3a¹,7,8,9,10,11,11b-decahydro-1H-pyrido[2,3,4-gh]phenanthridine-3a¹,4-dicarbonitrile 
• 1394901-96-2 2-(2-chlorophenyl)-9-fluoropyrrolo[2,3,4-kl]acridin-1(2H)-one 
• 1265900-21-7 3-[(2-chlorophenyl)(methyl)amino]cyclohex-2-enone 
• 1220515-93-4 3-[(2-chlorophenyl)(3-nitrophenyl)amino]-2-iodocyclohex-2-enone 
• 1220515-79-6 3-[(2-chlorophenyl)(phenyl)amino]-2-iodocyclohex-2-enone 
• 15128-52-6 1,2,3,9-tetrahydro-4H-carbazol-4-one 

Relevant articles and documents

Concurrent α-iodination and N-arylation of cyclic β-enaminones

A variety of N-substituted 3-aminocyclohex-2-enones were converted into the corresponding N-arylated α-iodo enaminones in high yields via concurrent N-iodination and N-arylation mediated by ArI(OAc)2. A mechanism is postulated to account for the reaction differences between the cyclic and the acyclic -enaminones, which undergo predominant β-acetoxylation under the same reaction conditions.

Process for the preparation of indoles

A process for the preparation of indoles, e.g. 1,2,3,9-tetrahydro-carbazol-4-one and derivatives thereof.