51415-34-0

Upstream product

• 66363-43-7 (2S,5R,6S)-benzyl 6-(1,3-dioxoisoindolin-2-yl)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 
• 551-16-6 6-Aminopenicillanic Acid 
• 182268-25-3 benzyl (2S)-2-[(3S,4R)-4-chloro-3-phthalimido-2-oxazetidin-1-yl]-2-(1-chlorothio-1-methylethyl)-acetate 
• 182268-32-2 benzyl (2S)-2-[(3R,4S)-4-chloro-3-phthalimido-2-oxazetidin-1-yl]-2-(1-chlorothio-1-methylethyl)-acetate 
• 20425-27-8 (2S,5R,6R)-6-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 
• 59034-26-3 (2S,5R,6R)-benzyl 6-(1,3-dioxoisoindolin-2-yl)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 
• 22509-74-6 N-ethoxycarbonylphthalimide 

Downstream Products

• 107668-25-7 (R)-2-[(2R,3S)-3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-2-(2-methoxycarbonyl-ethanesulfinyl)-4-oxo-azetidin-1-yl]-3-methyl-but-3-enoic acid benzyl ester 
• 107645-26-1 (R)-2-[(2R,3S)-3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-2-(2-methoxycarbonyl-ethylsulfanyl)-4-oxo-azetidin-1-yl]-3-methyl-but-3-enoic acid benzyl ester 
• 107668-26-8 (R)-2-[(2R,3S)-3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-2-(2-methoxycarbonyl-ethylsulfanyl)-4-oxo-azetidin-1-yl]-3-methyl-butyric acid benzyl ester 
• 107645-27-2 (R)-2-[(2R,3S)-3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-2-fluoro-4-oxo-azetidin-1-yl]-3-methyl-butyric acid benzyl ester 
• 107740-87-4 (R)-2-[(2R,3R)-3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-2-fluoro-4-oxo-azetidin-1-yl]-3-methyl-butyric acid benzyl ester 

Relevant academic research and scientific papers

Syntheses of (6S)-cephalosporins from 6-aminopenicillanic acid

Two practical routes to (6S,7S)-cephalosporins from 6-aminopenicillanic acid (6-APA) are described. In the first, 6-APA was converted to (2S,4S,5S,6S)-penicillin sulfoxide 49, which underwent Morin ring expansion to a protected (6S,7S)-cephem 50. In the s

4-FLUOROAZETIDINONE DERIVATIVES FROM SECOPENICILLANATE SULPHONIUM TETRAFLUOROBORATES

Reaction of certain secopenicillanate esters with trimethyloxonium tetrafluoroborate yielded 4-fluoroazetidinone derivatives presumably via the intermediacy of secopenicillanate sulphonium tetrafluoroborate salts.