51417-51-7Relevant articles and documents
7-Pyridylindoles: Synthesis, structure, and properties
Mudadu, Maria Salvatora,Singh, Ajay,Thummel, Randolph P.
, p. 7611 - 7617 (2006)
(Chemical Equation Presented) A series of three isomeric 7-pyridylindoles (7-PIs) are prepared where the pyridine attachment is through C2, C3, or C4. These systems are prepared by a combination of the Bartoli reaction and the Stille coupling with an appropriate pyridyl stannane. By treatment with CH 3I, the 7-PIs can be converted to their pyridinium salts. Deprotonation at the NH of these salts leads to a zwitterion which, in the 4-pyridyl system, also exists as a neutral isomer. The photophysical and NMR properties of these systems are discussed. All three pyridylindoles are analyzed by X-ray crystallography and shown to exist in different states of aggregation dictated by the formation of intra- and intermolecular H-bonds.
CONDENSED HETEROAROMATIC RING SYSTEMS. XXIII. A CONCISE SYNTHESIS OF HIPPADINE
Sakamoto, Takao,Yasuhara, Akito,Kondo, Yoshinori,Yamanaka, Hiroshi
, p. 2597 - 2600 (1993)
Hippadine, a pyrrolophenanthridine alkaloid, was synthesized in 39percent overall yield of three steps using the palladium-catalyzed cross-coupling reaction of 2,6-dibromoaniline with (Z)-1-tributylstannyl-2-ethoxyethene as a key step.
Rh(III)-Catalyzed Selective C7 Halogenation of Indolines
Manisha,Gupta, Shiv Shankar,Dhiman, Ankit Kumar,Sharma, Upendra
, p. 5443 - 5448 (2021/10/25)
An efficient Rh-catalyzed catalytic method has been developed for selective C7 halogenation of N-pyrimidyl indolines with N-halosuccinimides (Cl, Br, I) to produce corresponding halides in good to excellent yields. The advantages of this strategy include
Pd-Catalyzed C-H Halogenation of Indolines and Tetrahydroquinolines with Removable Directing Group
Ahmad, Ashfaq,Dutta, Himangsu Sekhar,Kumar, Mohit,Khan, Afsar Ali,Raziullah,Koley, Dipankar
, p. 5870 - 5875 (2020/07/30)
Pd-catalyzed directing-group-assisted regioselective halogenations to C7 of indolines and C8 of tetrahydroquinolines were achieved in good to excellent yields. The practicality and utility of the developed method have been illustrated by various functiona