51422-00-5 Usage
Uses
Used in Pharmaceutical Industry:
Pyrimidine, 4-chloro-2-fluoro(9CI) is used as a building block for the synthesis of various biologically active compounds. Its unique structure and halogenated nature make it a valuable component in the development of new drugs with diverse therapeutic properties.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, Pyrimidine, 4-chloro-2-fluoro(9CI) is employed as a key intermediate in the synthesis of novel drug candidates. Its reactivity and structural versatility allow researchers to explore various chemical modifications and functionalizations, leading to the discovery of new therapeutic agents with improved efficacy and selectivity.
Used in Drug Development:
Pyrimidine, 4-chloro-2-fluoro(9CI) is utilized in the development of new drugs targeting a wide range of diseases and conditions. Its incorporation into drug molecules can enhance their pharmacokinetic and pharmacodynamic properties, such as solubility, stability, and bioavailability, ultimately contributing to the success of drug candidates in clinical trials and eventual market approval.
Used in Chemical Synthesis:
Beyond its applications in the pharmaceutical industry, Pyrimidine, 4-chloro-2-fluoro(9CI) can also be employed in various chemical synthesis processes. Its unique reactivity and functional groups make it a valuable component in the preparation of other organic compounds, including agrochemicals, dyes, and materials with specific properties.
Check Digit Verification of cas no
The CAS Registry Mumber 51422-00-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,4,2 and 2 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 51422-00:
(7*5)+(6*1)+(5*4)+(4*2)+(3*2)+(2*0)+(1*0)=75
75 % 10 = 5
So 51422-00-5 is a valid CAS Registry Number.
51422-00-5Relevant academic research and scientific papers
Selective fluorination by halogen exchange of chlorodiazines and chloropyridines promoted by the 'proton sponge' - Triethylamine tris(hydrogen fluoride) system
Darabantu, Mircea,Lequeux, Thierry,Pommelet, Jean-Claude,Plé, Nelly,Turck, Alain
, p. 739 - 750 (2007/10/03)
The 'proton sponge' - triethylamine tris(hydrogen fluoride) mixtures provide a mild and efficient fluorinating reagent to introduce selectively fluorine atoms by halogen exchange into chlorodiazines and chloronitropyridine series.
The proton sponge-triethylamine tris(hydrogen fluoride) system as a selective nucleophilic fluorinating reagent for chlorodiazines
Darabantu, Mirce,Lequeux, Thierry,Pommelet, Jean-Claude,Plé, Nelly,Turck, Alain,Toupet, Lo?c
, p. 6763 - 6767 (2007/10/03)
The proton sponge-triethylamine tris(hydrogen fluoride) mixture provides a mild and efficient fluorinating - reagent for the selective introduction of a fluorine atom, by halogen exchange, into dichlorodiazines. (C) 2000 Elsevier Science Ltd.
