51433-10-4

Upstream product

• 100-44-7 benzyl chloride 
• 70144-57-9 methyl 4,6-O-benzylidene-3-O-methyl-β-D-glucopyranoside 
• 15038-71-8 methyl 2-O-benzyl-4,6-O-benzylidene-α-D-glucopyranoside 
• 74-88-4 methyl iodide 
• 14982-01-5 methyl 3-O-methyl-β-D-glucopyranoside 

Downstream Products

• 150412-64-9 p-nitrophenyl 2,4,6-tri-O-acetyl-3-O-methyl-α-D-glucopyranoside 
• 150412-65-0 p-nitrophenyl 3-O-methyl-α-D-glucopyranoside 

Relevant academic research and scientific papers

Synthesis of monomethyl derivatives of p-nitrophenyl α-d-gluco, galacto, and mannopyranosides and their hydrolytic properties against α-glycosidases

All possible monomethyl derivatives of p-nitrophenyl α-D-gluco, galacto, and mannopyranosides were synthesized. Hydrolytic activities of α-glucosidase (rice), α-galactosidases (green coffee bean, Mortierella vinacea, and Aspergillus niger), and α-mannosidases (almond and jack bean) against them were elucidated. The 6-O-methyl galactopyranoside and mannopyranoside were hydrolyzed by the M. vinacea α-galactosidase and the almond and jack bean α-mannosidases, respectively, while these enzymes did not act on the 2-, 3-, and 4-O-methyl derivatives. On the other hand, rice α-glucosidase and green coffee bean and A. niger α-galactosidases had no hydrolyzing activities at all against the respective four monomethylated substrates.