51446-87-8

Upstream product

• 91-01-0 1,1-Diphenylmethanol 
• 4052-54-4 Penicillin G 1-(s)-oxide 
• 908093-98-1 diazodiphenylmethane 
• 67565-52-0 diphenylmethyl 6β-(2-phenylacetamido)penicillanate 
• 66363-41-5 (S)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzhydryl ester 
• 114-70-5 sodium phenylacetate 
• 101760-73-0 (2S,5R,6R)-6-(Bis-phenylacetyl-amino)-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzhydryl ester 
• 101760-76-3 (2S,4R,5R,6R)-6-(Bis-phenylacetyl-amino)-3,3-dimethyl-4,7-dioxo-4λ⁴-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzhydryl ester 

Downstream Products

• 78037-13-5 (R)-2-((1S,5R)-3-Benzyl-7-oxo-4-oxa-2,6-diaza-bicyclo[3.2.0]hept-2-en-6-yl)-3-methyl-but-3-enoic acid benzhydryl ester 
• 157584-72-0 (R)-2-[(2R,3R)-2-(Benzooxazol-2-yldisulfanyl)-4-oxo-3-phenylacetylamino-azetidin-1-yl]-3-methyl-but-3-enoic acid benzhydryl ester 
• 130164-50-0 (R)-2-{(2R,3R)-2-[(2R,3R)-1-((R)-1-Benzhydryloxycarbonyl-2-methyl-propyl)-4-oxo-3-phenylacetylamino-azetidin-2-yldisulfanyl]-4-oxo-3-phenylacetylamino-azetidin-1-yl}-3-methyl-butyric acid benzhydryl ester 
• 130164-51-1 (R)-2-{(2R,3R)-2-[(2R,3R)-1-((R)-1-Carboxy-2-methyl-propyl)-4-oxo-3-phenylacetylamino-azetidin-2-yldisulfanyl]-4-oxo-3-phenylacetylamino-azetidin-1-yl}-3-methyl-butyric acid 
• 130164-49-7 (R)-2-((1R,5R)-3-Benzyl-7-oxo-4-thia-2,6-diaza-bicyclo[3.2.0]hept-2-en-6-yl)-3-methyl-butyric acid benzhydryl ester 
• 4052-54-4 Penicillin G 1-(s)-oxide 
• 119944-09-1 (R)-2-((1R,5R)-3-Benzyl-7-oxo-4-thia-2,6-diaza-bicyclo[3.2.0]hept-2-en-6-yl)-3-methyl-but-3-enoic acid benzhydryl ester 

Relevant academic research and scientific papers

Penicillin G sulfoxide diphenyl methyl ester synthesis method

The invention discloses a penicillin G sulfoxide diphenyl methyl ester synthesis method, which comprises: esterifying a penicillin G potassium salt as an initial raw material, and oxidizing through 2KHSO5.KHSO4.K2SO4 to synthesize the penicillin G sulfoxi

CONCERNING THE INTERMEDIACY OF MONOCYCLIC β-LACTAMS IN PENICILLIN BIOSYNTHESIS: SYNTHESIS AND ATTEMPTED BIOCONVERSION OF SECO-ISOPENICILLIN N

The title compound (3a) was synthesized as its dimer by the skeletal rearrangement of protected isopenicillin N-sulfoxide, hydrogenation, hydrolysis of the thiazoline ring, oxidative dimerization and deprotection.The reductive conversion of the dimer to m

2,4,6-TRIPYRIDINIO-1,3,5-TRIAZINE TRICHLORIDE, A NEW AND MILD ESTERIFICATION AGENT FOR PREPARATION OF PENICILLIN ESTERS

Cyanuric chloride reacted with 3-molar equivalents of pyridine to give 2,4,6-tripyridinio-1,3,5-triazine trichloride, which was found to condense penicilins with alcohols under mild conditions to afford penicillin esters in good yields.Application to prep

Oxidation Studies on β-Lactam Antibiotics. The 6-(Diacylamino)penicillins

The oxidation of the 6-(diacylamino)penicillins is a convenient, high yield route to the penicillin 1α-sulfoxides.The yield of the 1α-sulfoxide is dependent on the solvent, the temperature, the C-3 ester function, and the substituent at the C-2 position.T

Process for the preparation of esters of N-blocked penicillin acids which comprises reacting the acid or a salt thereof with a primary amine and a nitrosating agent

A process is described for the preparation of esters of N-blocked amino acids (such as penicillins or cephalosporins) wherein the amino acid or a salt thereof is reacted with a primary amine and nitrosating agent.