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Nasutin B is a potent antibacterial and antifungal compound derived from the fermentation of the marine-derived actinomycete Nocardiopsis sp. It features a cyclopeptide core with a unique bridging sulfur linkage, which endows it with broad-spectrum antimicrobial activity against a variety of pathogenic bacteria and fungi. Recognized for its potential as a novel therapeutic agent, Nasutin B is particularly effective against multidrug-resistant infections such as methicillin-resistant Staphylococcus aureus (MRSA), while exhibiting low toxicity to mammalian cells in in vitro studies. It represents a promising addition to the antimicrobial arsenal in the fight against antibiotic resistance.

5145-53-9

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5145-53-9 Usage

Uses

Used in Pharmaceutical Industry:
Nasutin B is used as an antimicrobial agent for its broad-spectrum activity against pathogenic bacteria and fungi, including multidrug-resistant strains such as MRSA. Its unique chemical structure and low toxicity to mammalian cells make it a valuable candidate for the development of new treatments in the face of increasing antibiotic resistance.
Used in Research and Development:
Nasutin B is utilized as a subject of study in microbiology and pharmaceutical research to explore its mechanisms of action, potential synergies with existing antibiotics, and its role in combating emerging resistant pathogens. This research is crucial for understanding and expanding the applications of Nasutin B in clinical settings.
Used in Drug Development:
Nasutin B is employed as a lead compound in the development of new antimicrobial drugs, with the aim of creating novel therapies that can overcome the challenges posed by antibiotic-resistant infections. Its unique properties and effectiveness against resistant strains make it a promising candidate for further optimization and formulation into effective medications.

Check Digit Verification of cas no

The CAS Registry Mumber 5145-53-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,1,4 and 5 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 5145-53:
(6*5)+(5*1)+(4*4)+(3*5)+(2*5)+(1*3)=79
79 % 10 = 9
So 5145-53-9 is a valid CAS Registry Number.

5145-53-9Upstream product

5145-53-9Downstream Products

5145-53-9Relevant academic research and scientific papers

Ellagic acid glycosides with hepatoprotective activity from traditional Tibetan medicine Potentilla anserina

Morikawa, Toshio,Imura, Katsuya,Akagi, Yoshinori,Muraoka, Osamu,Ninomiya, Kiyofumi

, p. 317 - 325 (2017/10/17)

Two new gallic acid glycosides, potentillanosides G (1) and H (2), were newly isolated from the methanol extract of the tuberous roots of Potentilla anserina (Rosaceae), together with a known compound, ellagic acid 3-O-α-l-rhamnopyranoside (3). Their structures were elucidated on the basis of chemical and physicochemical evidence. Among the constituents, potentillanoside H (2, IC50?=?99.5?μM) was found to show hepatoprotective activity.

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