5145-95-9

Upstream product

• 611-99-4 4,4'-Dihydroxybenzophenone 
• 106-89-8 epichlorohydrin 

Downstream Products

• 166596-81-2 C₂₅H₂₆O₉ 
• 1314090-49-7 C₁₉H₂₀Cl₂O₅ 

Relevant academic research and scientific papers

BISPHENOL DERIVATIVE THERAPEUTICS AND METHODS FOR THEIR USE

This invention provides compounds having a structure of Formula (I). Uses of such compounds for treatment of various indications, including prostate cancer as well as methods of treatment involving such compounds are also provided.

Synthesis, characterization, and thermal properties of diacrylic/ divinylbenzene copolymers

In this article, synthesis, characterization, and thermal properties of diacrylic/divinylbenzene copolymers based on the new aromatic tetrafunctional acrylate monomers are presented. The new monomers were generated by treatment of epoxides derived from various aromatic diols: naphthalene-2,3-diol (NAF), biphenyl-4,4′-diol (BIF), bis(4-hydroxyphenyl)methanone (BEP) or 4,4′-thiodiphenol (BES), and epichlorohydrin with acrylic acid. The addition reaction was carried out by a ratio of 0.5 mol of suitable epoxy derivative and 1 mol of acrylic acid in the presence of 0.7 wt% of triethylbenzylammonia chloride (TEBAC) as a catalyst and 0.045 wt% of hydroquinone as a polymerization inhibitor. The chemical structure of the prepared acrylate monomers was confirmed by 13C NMR and GC MS spectra. The emulsion-suspension polymerization of acrylate monomers with divinylbenzene (DVB) in the presence of pore-forming diluents (toluene + decan-1-ol) allowed obtaining microspheres containing pendant functional groups (hydroxyl groups). This process was carried out at constant mol ratio of acrylate monomers: DVB (1:1), and constant volume ratio of pore-forming diluents to monomers (1:1). The different concentrations of toluene in the mixture with decan-1-ol were used for qualifying the effect of the diluents on the microsphere characteristics. The influence of synthesis's parameters on the properties of copolymer beads, e.g., pore size and surface area by BET method, the surface texture by AFM, swelling behavior in polar and non-polar solvents as well as thermal stability by differential scanning calorimetry (DSC), and thermogravimetric analysis (TG) was studied and discussed.

Synthesis of novel poly(hydroxyether terephthalate) via polyaddition of 2,5-difluoroterephthalic acid with aromatic bis(epoxide)s

A novel and more reliable synthetic route to 2,5-difluoroterephthalic acid was developed. A series of new poly(hydroxyether terephthalate) were prepared by the polyaddition of 2,5-difluoroterephthalic acid with various aromatic bis(epoxide)s catalyzed by tetrabutyl ammonium bromide.