51467-70-0

Basic information

• Product Name: 2,4,6-Trimethylpyridin-3-amine
• Synonyms: 2,4,6-TRIMETHYLPYRIDIN-3-AMINE;2.4.6-TRIMETHYL-3-AMINOPYRIDINE;3-pyridinamine, 2,4,6-trimethyl-;(2,4,6-trimethyl-3-pyridyl)amine;2,4,6-trimethyl-pyridin-3-ylamine;2,4,6-trimethylpyridin-3-amine(SALTDATA: FREE);3-aMino-2,4,6-triMethylpyridine
• CAS NO: 51467-70-0
• Molecular Formula: C₈H₁₂N₂
• Molecular Weight: 136.19
• Mol File: 51467-70-0.mol
• Article Data: 5

Chemical Properties

• Melting Point: 66 °C
• Boiling Point: 256.4 °C at 760 mmHg
• Flash Point: 132.6 °C
• Appearance: /
• Density: 1.018 g/cm³
• PKA: 8.26±0.18(Predicted)
• CAS DataBase Reference: 2,4,6-Trimethylpyridin-3-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,6-Trimethylpyridin-3-amine(51467-70-0)
• EPA Substance Registry System: 2,4,6-Trimethylpyridin-3-amine(51467-70-0)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 26
• HazardClass: IRRITANT
• Hazardous Substances Data: 51467-70-0(Hazardous Substances Data)

Usage

General Description

2,4,6-Trimethylpyridin-3-amine, also known as 2835-06-5, is a chemical compound under the category of organic substances, specifically identified under the sub-category of pyridines and derivatives. As implied by its name, it contains nitrogen and holds functional amine groups, indicating its ability to partake in a wide range of chemical reactions, often utilized in chemical synthesis and research. It appears as a white or light yellow powder at room temperature. The safety and environmental implications of this compound are not well established, highlighting the necessity for careful handling and proper protocols when working with this substance. Its chemical formula is C8H12N2 and it has a molar mass of 136.194 g·mol?1.

InChI:InChI=1/C8H12N2/c1-5-4-6(2)10-7(3)8(5)9/h4H,9H2,1-3H3

Upstream product

• 21203-55-4 2,4,6-trimethyl-3-nitro-pyridine 
• 108-75-8 2,4,6-trimethyl-pyridine 

Downstream Products

• 112991-26-1 bis-benzenesulfonyl-(2,4,6-trimethyl-1-oxy-[3]pyridyl)-amine 
• 101289-54-7 N-benzenesulfonyl-N-(2,4,6-trimethyl-[3]pyridyl)-glycine 
• 101588-17-4 N-benzenesulfonyl-N-(2,4,6-trimethyl-[3]pyridyl)-glycine-methyl ester 
• 111526-27-3 N-(2,4,6-trimethyl-1-oxy-[3]pyridyl)-benzenesulfonamide 
• 34456-56-9 N-(2,4,6-trimethyl-pyridin-3-yl)-benzenesulfonamide 
• 101289-51-4 N-(4-acetoxy-2,4,6-trimethyl-4H-[3]pyridylidene)-benzenesulfonamide 

Relevant articles and documents

Microwave-assisted reduction of aromatic nitro compounds with novel oxo-rhenium complexes

The reduction of several aromatic nitro compounds to amines by means of the two novel catalytic systems ([IMes]2ReOBr3)/PhSiH3 and ([Py]3ReNOBr2)/PhSiH3 under microwave irradiation is here reported. These two systems were able to perform the reduction of nitro groups with higher TON and TOF when compared with previously reported systems based on oxo-rhenium core under standard heating, although they showed a lesser broad reaction scope compared with the known systems.

Synthesis, corticotropin-releasing factor receptor binding affinity, and pharmacokinetic properties of triazolo-, imidazo-, and pyrrolopyrimidines and -pyridines

The synthesis and CRF receptor binding affinities of several new series of N-aryltriazolo- and -imidazopyrimidines and -pyridines are described. These cyclized systems were prepared from appropriately substituted diaminopyrimidines or -pyridines by nitrous acid, orthoester, or acyl halide treatment. Variations of amino (ether) pendants and aromatic substituents have defined the structure-activity relationships of these series and resulted in the identification of a variety of high-affinity agents (K(i)'s 1 has been selected for further pharmacological studies that will be reported in due course.

THE EFFECT OF VICINAL METHYL GROUPS ON THE REDUCTION OF AROMATIC NITRO COMPOUNDS WITH LITHIUM ALUMINIUM HYDRIDE

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