51469-50-2

Usage

Uses

Used in Pharmaceutical Synthesis:
1-(4-chlorophenyl)non-1-en-3-one is used as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs with potential therapeutic benefits.
Used in Agrochemical Production:
In the agrochemical industry, 1-(4-chlorophenyl)non-1-en-3-one is utilized as a component in the production of various agrochemicals, which are essential for enhancing crop protection and yield.
Used in Fragrance and Flavor Industry:
1-(4-chlorophenyl)non-1-en-3-one is also employed as a building block in the creation of fragrance and flavor compounds, capitalizing on its distinctive sweet odor to enhance the sensory profiles of consumer products.
Safety and Handling:
It is crucial to handle 1-(4-chlorophenyl)non-1-en-3-one with caution due to its potential to cause irritation to the skin, eyes, and respiratory system. Additionally, proper storage is essential, as the compound should be kept in a cool, dry place away from heat and ignition sources, given its flammable nature.

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 111-13-7 hexyl-methyl-ketone 
• 1041849-94-8 1-(4-chlorophenyl)-2-nonyn-1-ol 
• 629-05-0 n-octyne 

Downstream Products

• 77921-27-8 1-(4-Chloro-phenyl)-1-ethylsulfanyl-nonan-3-one 
• 53710-42-2 (E)-1-(4-chlorophenyl)non-1-en-3-ol 
• 1428261-47-5 C₂₁H₂₁Cl₃N₂ 

Relevant academic research and scientific papers

Novel antiobesity agents: Synthesis and pharmacological evaluation of analogues of Rimonabant and of LH21

Searching for novel antiobesity agents, a series of cannabinoid LH21 and of Rimonabant-fatty acid amide analogues have been prepared. Synthesis of pyrazoles 2a-2c was achieved by a two steps simple methodology via α,β-unsaturated ketones. Carboxamides 8a-8h were obtained in good yields from esters 7a-7c by a one-pot procedure which takes place under mild conditions. New compounds have been evaluated in vivo as anorectic agents. Some of them showed interesting properties reducing food intake in rats by a mechanism which does not involve the endocannabinoid system.

Heteropoly compound catalyzed synthesis of both z- and e-α,β- unsaturated carbonyl compounds

An EZ switch: The cationic species of the heteropoly compounds has a critical impact on the Z/E selectivity of the Meyer-Schuster rearrangement of propargyl alcohols (see scheme). The isolation of the thermodynamically unfavorable Z-α,β-unsaturated carbonyl compounds is notable. The high Z selectivities were obtained at a reaction temperature as high as 50°C.