514793-45-4Relevant academic research and scientific papers
Synthesis and antimicrobial activity of novel thiazolidinone and azetidinone derivatives
Kshirsagar,Nimje,Chaudhari,Bayas,Patel,Karjikar,Girme,Oswal
, p. 4021 - 4023 (2012/01/12)
Reaction of 2,3-diketoquinoxaline in presence of phosphorus pentachloride and hydrazine hydrate gives 2-hydrazino-3-hydroxyquinoxalin (4) which on treatment with various aldehydes in appropriate solvent gives 2-p-anisyl-3-(3-hydroxy quinoxalin-2 yl-amino)-4-thiazolidinones (6) and 1-N-(3-hydroxy quinoxalin-2'yl-amino)-4-aryl-3-chloro-2-azetidinones (7). The structure of compounds 6a-6l and 7a-7l has been confirmed by IR and 1H NMR data. All these compounds were tested for their antimicrobial and antifungal activity against different microorganisms.
