51484-06-1 Usage
General Description
6-Bromochromone-2-carboxylic Acid is a synthetic, organic chemical compound made up of a chromone scaffold, which is basically a molecular structure commonly found in many pharmaceuticals and natural products. The presence of the bromine atom signifies that this compound belongs to the class of organobromides. Additionally, the carboxylic acid functional group suggests its potential to participate in various chemical reactions. 6-BROMOCHROMONE-2-CARBOXYLIC ACID can be used in chemical research and could offer valuable insight during drug discovery. It's important to note the need for proper handling and storage to maintain its stability and avoid hazardous decomposition. As of now, it has not been classified under any specific industrial use, and the data associated with its potential health effects or environmental impact is quite limited.
Check Digit Verification of cas no
The CAS Registry Mumber 51484-06-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,4,8 and 4 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 51484-06:
(7*5)+(6*1)+(5*4)+(4*8)+(3*4)+(2*0)+(1*6)=111
111 % 10 = 1
So 51484-06-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H5BrO4/c11-5-1-2-8-6(3-5)7(12)4-9(15-8)10(13)14/h1-4H,(H,13,14)
51484-06-1Relevant articles and documents
Optimizing the synthetic route of chromone-2-carboxylic acids: A step forward to speed-up the discovery of chromone-based multitarget-directed ligands
Cagide, Fernando,Oliveira, Catarina,Reis, Joana,Borges, Fernanda
, (2019)
6-Bromochromone-2-carboxylic acid (3) was synthesized by a microwave-assisted process. The optimization of the reaction was performed varying parameters, such as type of base/number of reagent equivalents, solvent, temperature and reaction time. The yield of the reaction was improved to 87%. The new synthetic route is versatile as several chromone-2-carboxylic acids (compounds 4B-10B) were obtained with good yields (54-93%). Only in the case of the nitro substituent (compound 11B), an ester was obtained instead of the desired carboxylic acid. Following this synthetic route chromone carboxylic acids can be attained with a high degree of purity, without the need of the tedious and expensive purification processes through column chromatography. The reaction is safe, cost-effective, fast and robust, and can be used in the development of concise and diversity-oriented libraries based on chromone scaffold. The overall study can be looked as a step forward to speed-up the discovery of chromone-based multitarget-directed ligands.
