514844-72-5Relevant academic research and scientific papers
Dearomatizing cyclization of arylsulfonylalkoxymethyl lithiums: A route to the podophyllotoxin skeleton
Clayden, Jonathan,Kenworthy, Martin N.,Helliwell, Madeleine
, p. 831 - 834 (2007/10/03)
(Matrix presented) The phenylsulfonyl group promotes the dearomatizing cyclization of tethered organolithiums onto aromatic rings. With an ether tether, the cyclizations create a new tetrahydrofuran ring, and both cyclization and subsequent electrophilic
