514854-12-7 Usage
General Description
2,4-Pyrimidinediamine, 6-ethyl- is a chemical compound with the molecular formula C7H10N4. It is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. This chemical is a white to pale yellow solid, and it is soluble in organic solvents such as ethanol and acetone. 2,4-Pyrimidinediamine, 6-ethyl- is also known by the trade names Ethyl Pyrimidindiamine and 6-EAPD. It is important to handle this chemical with care as it may cause skin and eye irritation and should be stored in a cool, dry place away from heat and sources of ignition.
Check Digit Verification of cas no
The CAS Registry Mumber 514854-12-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,1,4,8,5 and 4 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 514854-12:
(8*5)+(7*1)+(6*4)+(5*8)+(4*5)+(3*4)+(2*1)+(1*2)=147
147 % 10 = 7
So 514854-12-7 is a valid CAS Registry Number.
InChI:InChI=1/C6H10N4/c1-2-4-3-5(7)10-6(8)9-4/h3H,2H2,1H3,(H4,7,8,9,10)
514854-12-7Relevant articles and documents
Structural studies on bioactive compounds. Part 37. Suzuki coupling of diaminopyrimidines: A new synthesis of the antimalarial drug pyrimethamine
Richardson, Marianne L.,Stevens, Malcolm F.G.
, p. 482 - 484 (2007/10/03)
Suzuki reactions have been used successfully to effect cross-coupling of 5-halopyrimidines with 4-chlorobenzeneboronic acid and 2,4-diamino-5-(4-chloro-3-halo)-6-ethylpyrimidines with 4-methoxybenzeneboronic acid. The antimalarial drug pyrimethamine has been prepared by coupling 2,4-diamino-6-ethyl-5-iodopyrimidine with 4-chlorobenzeneboronic acid.
