51504-01-9Relevant academic research and scientific papers
Side-Chain Modified Ergosterol and Stigmasterol Derivatives as Liver X Receptor Agonists
Marinozzi, Maura,Castro Navas, Francisco Fermin,Maggioni, Daniela,Carosati, Emanuele,Bocci, Giovanni,Carloncelli, Maria,Giorgi, Gianluca,Cruciani, Gabriele,Fontana, Raffaella,Russo, Vincenzo
, p. 6548 - 6562 (2017)
A series of stigmasterol and ergosterol derivatives, characterized by the presence of oxygenated functions at C-22 and/or C-23 positions, were designed as potential liver X receptor (LXR) agonists. The absolute configuration of the newly created chiral ce
SIDE-CHAIN MODIFIED ERGOSTEROL AND STIGMASTEROL DERIVATIVES AS LIVER X RECEPTOR MODULATORS
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Page/Page column 38; 39, (2019/02/13)
The present invention relates to novel Liver X Receptor (LXR) modulators, their use in diagnostic and therapy, more particularly in the treatment of diseases associated with LXR, such as cancer, inflammation, metabolic and autoimmune diseases.
SELECTIVE OXIDATION OF THE DOUBLE BONDS IN THE 4-PHENYL-1,2,4-TRIAZOLINE-3,5-DIONE DIELS-ALDER ADDUCT OF ERGOSTEROL ACETATE
Piatak, David M.,Swenson, Rebecca P.
, p. 93 - 100 (2007/10/02)
Methods for oxidations at the 6(7)-and 22(23)-double bonds in the phenyltriazoline adduct of ergosterol acetate (I) are described.KMnO4 and OsO4 were found to react with the 6(7)-double bond to yield the 6,7-glycol and osmate ester, respectively.Other rea
