51508-05-5Relevant academic research and scientific papers
A series of novel aryl-methanone derivatives as inhibitors of FMS-like tyrosine kinase 3 (FLT3) in FLT3-ITD-positive acute myeloid leukemia
Sellmer, Andreas,Pilsl, Bernadette,Beyer, Mandy,Pongratz, Herwig,Wirth, Lukas,Elz, Sigurd,Dove, Stefan,Henninger, Sven Julian,Spiekermann, Karsten,Polzer, Harald,Klaeger, Susan,Kuster, Bernhard,B?hmer, Frank D.,Fiebig, Heinz-Herbert,Kr?mer, Oliver H.,Mahboobi, Siavosh
, (2020)
Mutants of the FLT3 receptor tyrosine kinase (RTK) with duplications in the juxtamembrane domain (FLT3-ITD) act as drivers of acute myeloid leukemia (AML). Potent tyrosine kinase inhibitors (TKi) of FLT3-ITD entered clinical trials and showed a promising,
Tetrazolinone derivatives
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, (2008/06/13)
Herbicidal novel tetrazolinone derivatives of the formula: STR1 wherein R1 is alkyl, haloalkyl, cycloalkyl, alkenyl, haloalkenyl, alkynyl, alkoxy or phenyl which is optionally substituted, and R2 is alkyl, haloalkyl, cycloalkyl, alkenyl, haloalkenyl, alkynyl, alkoxy or phenyl which is optionally substituted, or R1 and R2 form, together with the nitrogen atom to which R1 and R2 are bonded, a 5- or 6-membered heterocyclic ring, optionally fused to a carbocyclic ring optionally and independently substituted by C1-4 alkyl, and R3 is a 5-membered heterocyclic radical containing at least one hereto atom selected from the group consisting of nitrogen, oxygen, and sulfur, optionally substituted by at least one substitutent selected from the group consisting of halogen, benzyl, phenyl, halogen-substituted phenyl, C1-4 alkyl, C1-4 alkoxy, C1-4 haloalkyl, C1-4 haloalkoxy, C1-4 alkylthio, C1-4 alkyl-sulfonyl and C3-8 cycloalkyl, processes for their preparation and novel intermediates therefor.
New thiadiazolylimidazolidinone ester
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, (2008/06/13)
This invention discloses the compound 1-(5-t-butyl-1,3,4-thiadiazol-2-yl)-3,4-dimethyl-5-acetyloxy-1,3-imidazolidin-2-one and its use as a herbicide.
1-(5-T-BUTYL-1,3,4-THIADIAZOL-2-YL)-3-METHYL-5-OCTANOYLOXY-1,3-IMIDAZOLIDIN-2-ONE HERBICIDE
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, (2008/06/13)
This invention discloses the compound 1-(5-t-butyl-1,3,4-thiadiazol-2-yl)-3-methyl-5-octanoyloxy-1,3-imidazolidin-2-one and its utility as a herbicide.
1-(5-T-Butyl-1,3,4-thiadiazol-2-yl)-3-methyl-5-nonanoyloxy-1,3-imidazolidin-2-one herbicide
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, (2008/06/13)
This invention discloses the compound 1-(5-t-butyl-1,3,4-thiadiazol-2-yl)-3-methyl-5-nonanoyloxy-1,3-imidazolidin-2-one and its utility as a herbicide.
