515154-97-9Relevant academic research and scientific papers
Alkyne-quinuclidine derivatives as potent and selective muscarinic antagonists for the treatment of COPD
Starck, Jean-Philippe,Provins, Laurent,Christophe, Bernard,Gillard, Michel,Jadot, Sophie,Lo Brutto, Patrick,Quere, Luc,Talaga, Patrice,Guyaux, Michel
, p. 2675 - 2678 (2008/12/21)
SAR around alkyne-quinuclidine derivatives allowed the discovery of highly potent muscarinic antagonists displaying interesting preferential slow off-rates from the M3 receptor.
