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51516-96-2

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51516-96-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 51516-96-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,5,1 and 6 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 51516-96:
(7*5)+(6*1)+(5*5)+(4*1)+(3*6)+(2*9)+(1*6)=112
112 % 10 = 2
So 51516-96-2 is a valid CAS Registry Number.

51516-96-2Upstream product

51516-96-2Relevant articles and documents

Compositions for Treatment of Cystic Fibrosis and Other Chronic Diseases

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Paragraph 0397; 1632; 1744, (2015/09/22)

The present invention relates to pharmaceutical compositions comprising an inhibitor of epithelial sodium channel activity in combination with at least one ABC Transporter modulator compound of Formula A, Formula B, Formula C, or Formula D. The invention also relates to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis using the pharmaceutical combination compositions.

MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS

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Page/Page column 67, (2012/12/14)

The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.

Modulators of ATP-binding cassette transporters

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Page/Page column 110-111; 138, (2008/06/13)

Compounds of the present invention and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.

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