51528-18-8Relevant academic research and scientific papers
Pyridine-catalyzed double C-N coupling reaction of an isocyanate with two benzynes
Lee, Yi-Hsien,Chen, Yen-Chung,Hsieh, Jen-Chieh
supporting information; experimental part, p. 247 - 250 (2012/02/04)
A pyridine-catalyzed double C-N bond cross-coupling reaction involving two benzynes with an isocyanate was carried out. The coupling reaction proceeded through a unique pathway involving the formation of an unstable carbamic acid intermediate and facile decarboxylation. Subsequent nucleophilic addition/protonation of in situ prepared amines with benzynes afforded variously substituted diaryl- and triarylamines in moderate to good yields with tolerance of a variety of functional groups. Copyright
