5153-25-3

Usage

Uses

Used in Cosmetics and Personal Care Industry:
2-Ethylhexyl 4-hydroxybenzoate is used as a preservative for its ability to extend the shelf life of products by inhibiting the growth of bacteria and fungi, ensuring the safety and efficacy of cosmetics and personal care items over time.
Used in Sun Protection Products:
In the formulation of sunscreens and other sun protection products, 2-Ethylhexyl 4-hydroxybenzoate is used as a broad-spectrum UV filter to protect the skin and hair from the damaging effects of ultraviolet radiation, reducing the risk of sunburn and long-term skin damage.
Used in Antimicrobial Applications:
Beyond cosmetics, 2-Ethylhexyl 4-hydroxybenzoate is utilized as an antimicrobial agent in various industries, where it helps to prevent spoilage and contamination, maintaining the integrity and quality of products throughout their shelf life.

InChI:InChI=1/C15H22O3/c1-3-5-6-12(4-2)11-18-15(17)13-7-9-14(16)10-8-13/h7-10,12,16H,3-6,11H2,1-2H3

Synthetic route

2-Ethylhexyl alcohol (104-76-7) + 4-hydroxy-benzoic acid (99-96-7) → 2-ethyl-1-hexyl p-hydroxybenzoate (5153-25-3)

Conditions	Yield
With sulfuric acid; benzene Entfernen des entstehenden Wassers;

4-bromo-phenol (106-41-2) + 2-Ethylhexyl alcohol (104-76-7) → 2-ethyl-1-hexyl p-hydroxybenzoate (5153-25-3)

Conditions	Yield
With sodium carbonate; palladium-carbon

sulphur dichloride + zinc chloride anhydrate + 2-ethyl-1-hexyl p-hydroxybenzoate (5153-25-3) → 3,3'-thiobis(2-ethylhexyl p-hydroxybenzoate)

Conditions	Yield
In chloroform

BPA (80-05-7) + formaldehyd (50-00-0) + para-tert-butylphenol (98-54-4) + 2-ethyl-1-hexyl p-hydroxybenzoate (5153-25-3) → poly(2,2-bis(4-hydroxyphenyl)propane-co-p-t-butylphenol-co-2-ethylhexyl 4-hydroxybenzoate-co-formaldehyde)

Conditions	Yield
With potassium hydroxide In water; xylene for 8h; Heating / reflux;

formaldehyd (50-00-0) + para-tert-butylphenol (98-54-4) + 2-ethyl-1-hexyl p-hydroxybenzoate (5153-25-3) + 1,1-bis-(4-hydroxy-phenyl)-1-phenyl-propane (47252-81-3) → poly(4,4'-(1-phenylethylidene)bisphenol-co-p-t-butylphenol-co-co-2-ethylhexyl 4-hydroxybenzoate-co-formaldehyde)

Conditions	Yield
With potassium hydroxide In water; xylene for 8h; Heating / reflux;

formaldehyd (50-00-0) + 1,1-bis(4-hydroxyphenyl)cyclohexane (843-55-0) + para-tert-butylphenol (98-54-4) + 2-ethyl-1-hexyl p-hydroxybenzoate (5153-25-3) → poly(1,1-bis(4-hydroxyphenyl)cyclohexane-co-p-t-butylphenol-co-formaldehyde)

Conditions	Yield
With potassium hydroxide In water; xylene for 8h; Heating / reflux;

Upstream product

• 104-76-7 2-Ethylhexyl alcohol 
• 99-96-7 4-hydroxy-benzoic acid 
• 106-41-2 4-bromo-phenol 

Relevant academic research and scientific papers

Method for the manufacture of hydroxy aromatic monocarboxylic acids

A method for preparing hydroxy aromatic carboxylic acids, or the ester derivatives thereof, comprises the carbonylation of a hydroxy aromatic bromide in the presence of a catalytic amount of a transition element of group VIII of the Periodic Table on a carbon support, at a pH of above 8, in the absence of any promoter.The reaction is carried out at a temperature in the range of between 140oC to 200oC. The resulting products are obtained in high yields and of high purity. The method has particular applicability to the manufacture of 6-carboxy-2-naphthol and 4-hydroxy-4'-carboxy-biphenyl.