5154-10-9Relevant academic research and scientific papers
Synthesis and bioactivity of N-glycosylated 3-(2-oxo-2-arylethylidene)-indolin-2-ones
Kleeblatt, Dennis,Becker, Martin,Pl?tz, Michael,Sch?nherr, Madeleine,Villinger, Alexander,Hein, Martin,Eberle, Jürgen,Kunz, Manfred,Rahman, Qamar,Langer, Peter
, p. 20769 - 20782 (2015/03/30)
N-Glycosyl-3-alkylideneoxindoles, N-glycosylated 3-(2-oxo-2-arylethylidene)indolin-2-ones, were prepared by reaction of isatin-N-glycosides with substituted acetophenones. The biological activities of these new compounds revealed significant antitumor act
Synthesis and antiproliferative activity of N-glycosyl-3,3-diaryloxindoles
Kleeblatt, Dennis,Cordes, Christoph A.,Lebrenz, Philipp,Hein, Martin,Feist, Holger,Matin, Abdul,Raza, Rabia,Iqbal, Jamshed,Munshi, Omar,Rahman, Qamar,Villinger, Alexander,Langer, Peter
, p. 22828 - 22839 (2014/06/24)
N-Glycosylated 3,3-diaryloxindoles were prepared by Lewis acid catalyzed reaction of acetylated N-glycosylisatins with various benzene derivatives and subsequent deprotection. Some of the products showed antiproliferative activity against malignant cutane
Synthesis of thia-analogous indirubin n-glycosides and their influence onmelanoma cell growth and apoptosis
Kunz, Manfred,Driller, Katrin M.,Hein, Martin,Libnow, Stephanie,Hohensee, Ina,Ramer, Robert,Hinz, Burkhard,Berger, Anja,Eberle, Juergen,Langer, Peter
scheme or table, p. 534 - 539 (2010/12/25)
Stopping cancer in its tracks Thia-analogues of indirubin-N-glycosides, prepared by condensation of N-glycosylisatines with thiaindane-3-one and subsequent deprotection, were tested for their activity against malignant melanoma cells. These indirubin-N-gl
Nucleophilic catalysis of carbohydrate oxime formation by anilines
Thygesen, Mikkel B.,Munch, Henrik,Sauer, Jorgen,Clo, Emiliano,Jorgensen, Malene R.,Hindsgaul, Ole,Jensen, Knud J.
experimental part, p. 1752 - 1755 (2010/05/18)
("Figure Presented") Chemoselective formation of glycoconjugates from unprotected glycans is needed to further develop chemical biology involving glycans. Carbohydrate oxime formation is often slow, and organocatalysis by anilines would be highly promisin
First synthesis of indirubin N-glycosides (red sugars)
Libnow, Stefanie,Hein, Martin,Michalik, Dirk,Langer, Peter
, p. 6907 - 6909 (2007/10/03)
The first indirubin N-glycosides were prepared by reaction of isatine N-glycosides with indoxyl acetate under basic conditions.
Synthesis of fully protected N-arylglycosylamines and factors affecting the configuration of C1-substituents of N-arylglycosylamines
Du, Wenting,Hu, Yongzhou
, p. 2987 - 2992 (2007/10/03)
An efficient method was reported for preparation of N-arylglycosyl-amines in aqueous THF under reflux in good yields. The factors affecting the configuration of C1-substituents of N-aryglycosylamines was investigated, that is, the influence of
