51549-58-7Relevant academic research and scientific papers
A versatile and convenient regioselective acylation of 2'-deoxynucleosides and ribonucleosides by supported lipases of Pseudomonas Cepacia
Nair, Ranjeet V.,Salunkhe, Manikrao M.
, p. 3115 - 3120 (2000)
Pseudomonas Cepacia lipase supported on ceramic particles (lipase PS-C) and on diatomite (lipase PS-D) regioselectively acylated 2'-deoxynucleosides and ribonucleosides to 3'-O-acetyl-2'-deoxynucleosides and 3'-O-acetyl-ribonucleosides with oxime esters in organic solvents at room temperature. This enzymatic reaction was significant because the regioselectivity was total; as any other regioisomer nor the N-acylated product were observed.
