51552-27-3Relevant academic research and scientific papers
Chemoselective lactam formation in the addition of benzenesulfonyl bromide to N-allyl acrylamides and N-allyl 3,3-dimethylacrylamides
Wang,Russell
, p. 2346 - 2352 (1999)
Chemoselectivity in the addition and cyclization reactions of PhSO2Br to N-allyl acrylamides has been confirmed due to the higher reactivity of the acrylic C=C bond toward the sulfonyl radical than that of the allyl C=C bond. Formation of γ-lactams by C(β)→C(α) cyclization can be achieved with N- allyl 3,3-dimethylacrylamides.
