51570-20-8

Basic information

• Product Name: CHITOSANASE
• Synonyms: CHITOSANASE;CHITOSANASE, STREPTOMYCES SPECIES N174;CHITOSAN N-ACETYLGLUCOSAMINOHYDROASE;CHITOSAN N-ACETYLGLUCOSAMINOHYDROLASE;EC 3.2.1.132;chitosanase from streptomyces sp. N174;Chitosanase, Streptomyces sp.N174;CHITOSANASE FROM STREPTOMYCES SP. N174, RECOMBINANT
• CAS NO: 51570-20-8
• Molecular Weight: 0
• Mol File: 51570-20-8.mol
• Article Data: 0

Chemical Properties

• Appearance: /lyophilized powder
• Storage Temp.: −20°C
• Solubility: H2O: soluble, clear to slightly hazy, colorless (10U/0.3mL)
• CAS DataBase Reference: CHITOSANASE(CAS DataBase Reference)
• NIST Chemistry Reference: CHITOSANASE(51570-20-8)
• EPA Substance Registry System: CHITOSANASE(51570-20-8)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 51570-20-8(Hazardous Substances Data)

Usage

Description

Chitosanase, synthesized from Streptomyces griseus, is an extracellular secreted enzyme with a molecular weight of 34 kDa. It belongs to the glycosyl hydrolase family and has an α-helical tertiary structure similar to lysozyme, featuring a substrate-binding cleft between two lobes. Chitosanase exhibits optimal activity at a temperature of 60°C and a pH of 5.7. It is primarily involved in the enzymatic hydrolysis of chitin and chitosan, which are essential processes in various industries.

Uses

Used in Enzymatic Hydrolysis:
Chitosanase is used as an enzymatic catalyst for the hydrolysis of chitin and chitosan, which are biopolymers derived from the shells of crustaceans and cell walls of fungi. This hydrolysis process is crucial for the production of valuable compounds and materials in various industries.
Used in Pharmaceutical Industry:
Chitosanase is used as a digestive aid in the pharmaceutical industry, specifically for the digestion of lacrimal gland (LG) tissues. This application aids in the treatment and management of various health conditions related to the lacrimal gland.
Used in Research and Development:
Chitosanase is also utilized in research and development for the study of chitin and chitosan, as well as their potential applications in various fields. The enzyme's ability to hydrolyze these biopolymers allows for a better understanding of their properties and potential uses.
Used in Food Industry:
In the food industry, chitosanase can be employed for the modification of chitosan-based additives, improving their functional properties and enhancing the quality of the final products.
Used in Environmental Applications:
Chitosanase can be used in environmental applications, such as the biodegradation of chitin-rich waste materials, contributing to a more sustainable waste management system.
Used in Cosmetics Industry:
Chitosanase can be utilized in the cosmetics industry for the production of chitosan-based products, such as skincare and hair care products, which offer various benefits due to the unique properties of chitosan.

Biochem/physiol Actions

Chitosanase catalyzes the endohydrolysis of β-1,4-linkages between D-glucosamine (GlcN-GlcN) residues in chitosan. The enzyme from Streptomyces has been reported to also hydrolyze the GlcNAc-GlcN linkage in partially acetylated chitosan.